Table 1.

Susceptibility profiles conferred byaph(2")-Ib and/or aac(6′)-Im cloned in the vector pBluescript in E. coli DH5α

AminoglycosideMIC (μg/ml)
aph(2")-Ib +aac(6′)-Imaph(2")-Ibaac(6′)-ImDH5α(pBluescript)E. coli SCH92111602
Gentamicin64640.250.125128
Tobramycin512328.00.5256
Amikacin322.08.00.2532
Neomycin2.00.51.00.51.0
Dibekacin51232160.5≥512
Netilmicin128644.00.12564
Kanamycin A≥2,048512640.5≥512
Arbekacin4.04.00.250.1254.0