Table 1.

Clinical data of 17 cefozopran-resistant N. gonorrhoeae isolatesa

Strain no.Hospital IDbAge (yr) and sex of patientcFirst treatmentFinal treatment
AgentsdRegimeneClinical outcomeAgent(s)RegimenClinical outcome
SNG27Ue27, MCDR100 mg × 3, p.o., 3 daysFailureCRO1 g i.v., single doseCure
SPX100 mg, 3 days
SNG28Ya24, MSPT2 g i.m., single doseCure
DOX100 mg × 2, p.o., 7 days
SNG32Ar19, FCMSuppository, 2 timesNot tested
SNG33UO29, MAZT1 g i.v., single doseFailureSPT2 g i.m., single doseCure
SNG46Ya21, MSPT2 g i.m., single doseCure
DOX100 mg × 2, p.o., 7 days
SNG50Ni19, MCDR100 mg × 3, p.o., 3 daysFailureSPT2 g i.m., single doseNF
SNG52An22, FAMO375 mg × 4, p.o., 7 daysFailureCDZ1 g i.v., single doseCure
SNG53Kr24, MCRO1 g i.v., single doseCure
SNG54AY42, MLVX100 mg × 3, p.o.FailureCDZ1 g i.v., single doseCure
SNG57BM36, MUnknown
SNG65Ni19, MCDR100 mg × 3, 3 daysNFf
SNG70BM33, MUnknown
SNG74Ni30, MSPT2 g i.m., single doseCure
MIN100 mg × 2, 7 days
SNG75Ni27, MSPT2 g i.m., single doseCure
MIN100 mg × 2, p.o., 7 days
SNG76Ni29, MCDZ1 g i.v., single doseCure
SNG79Ni26, MCDZ1 g i.v., single doseCure
SNG81An19, MCDZ1 g i.v., single doseCure
  • a Including isolates from clinical failure cases treated with CDR and AZT. Data for SNG27 and SNG33 have been previously reported (1).

  • b Blind names of hospitals.

  • c M, male; F, female.

  • d CDR, cefdinir; DOX, doxycycline; MIN, minocycline; AMO, amoxicillin; SPX, sparfloxacin.

  • e p.o., orally; i.m., intramuscularly; i.v., intravenously.

  • f NF, not followed.