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acute bacterial skin and skin structure infections

  • Open Access
    Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study of the Effects of Omadacycline on QT/QTc Intervals in Healthy Subjects
    Mechanisms of Action: Physiological Effects
    Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study of the Effects of Omadacycline on QT/QTc Intervals in Healthy Subjects

    Omadacycline, an aminomethylcycline, is an antibiotic that is approved in the United States for once-daily intravenous (i.v.) and oral use for treatment of adults with acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.

    Borje Darpo, Hongqi Xue, S. Ken Tanaka, Evan Tzanis
  • Clinical Therapeutics
    A Phase 3, Randomized, Double-Blind, Multicenter Study To Evaluate the Safety and Efficacy of Intravenous Iclaprim versus Vancomycin for Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed To Be Due to Gram-Positive Pathogens (REVIVE-2 Study)
    Thomas L. Holland, William O'Riordan, Alison McManus, Elliot Shin, Ali Borghei, Thomas M. File, Mark H. Wilcox, Antoni Torres, Matthew Dryden, Thomas Lodise, Toyoko Oguri, G. Ralph Corey, Patrick McLeroth, Rajesh Shukla, David B. Huang
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