acyclovir

Antiviral Agents
Differences in the Likelihood of Acyclovir Resistance-Associated Mutations in the Thymidine Kinase Genes of Herpes Simplex Virus 1 and Varicella-Zoster Virus
Acyclovir (ACV) resistance-associated mutations in two recombinant herpes simplex virus 1 (HSV-1) clones were compared. Recombinant HSV-1 lacking its thymidine kinase (TK) and expressing varicella-zoster virus (VZV) TK ectopically had no mutations in the VZV TK gene.

Hikaru Fujii, Shizuko Harada, Tomoki Yoshikawa, Souichi Yamada, Natsumi Omura, Miho Shibamura, Takuya Inagaki, Hirofumi Kato, Shuetsu Fukushi, Masayuki Saijo
Pharmacology
Pharmacokinetics of Acyclovir and Its Metabolites in Cerebrospinal Fluid and Systemic Circulation after Administration of High-Dose Valacyclovir in Subjects with Normal and Impaired Renal Function
James P. Smith, Stephen Weller, Benjamin Johnson, Janet Nicotera, James M. Luther, David W. Haas
Antiviral Agents
Population Pharmacokinetics of Acyclovir in Children and Young People with Malignancy after Administration of Intravenous Acyclovir or Oral Valacyclovir
L. Zeng, C. E. Nath, E. Y. L. Blair, P. J. Shaw, K. Stephen, J. W. Earl, J. C. Coakley, A. J. McLachlan
Antiviral Agents
Pharmacokinetics of Acyclovir after Intravenous Infusion of Acyclovir and after Oral Administration of Acyclovir and Its Prodrug Valacyclovir in Healthy Adult Horses
B. Garré, K. Shebany, A. Gryspeerdt, K. Baert, K. van der Meulen, H. Nauwynck, P. Deprez, P. De Backer, S. Croubels
Antiviral Agents
Thymidine Kinase Mutations Conferring Acyclovir Resistance in Herpes Simplex Type 1 Recombinant Viruses
Yan Sergerie, Guy Boivin
Antiviral Agents
Early Selection of a New UL97 Mutant with a Severe Defect of Ganciclovir Phosphorylation after Valaciclovir Prophylaxis and Short-Term Ganciclovir Therapy in a Renal Transplant Recipient
Sébastien Hantz, Detlef Michel, Anne-Marie Fillet, Vincent Guigonis, Gaël Champier, Marie-Christine Mazeron, Albert Bensman, François Denis, Thomas Mertens, Axelle Dehee, Sophie Alain
Antiviral Agents
Herpes Simplex Virus Thymidine Kinase Mutations Associated with Resistance to Acyclovir: a Site-Directed Mutagenesis Study
E. Frobert, T. Ooka, J. C. Cortay, B. Lina, D. Thouvenot, F. Morfin
Antiviral Agents
Susceptibilities of Several Clinical Varicella-Zoster Virus (VZV) Isolates and Drug-Resistant VZV Strains to Bicyclic Furano Pyrimidine Nucleosides
Graciela Andrei, Rebecca Sienaert, Chris McGuigan, Erik De Clercq, Jan Balzarini, Robert Snoeck
Antiviral Agents
Acyclovir Levels in Serum and Cerebrospinal Fluid after Oral Administration of Valacyclovir
Jan Lycke, Clas Malmeström, Lars Ståhle
Antiviral Agents
Intra- and Interindividual Variabilities of Valacyclovir Oral Bioavailability and Effect of Coadministration of an hPEPT1 Inhibitor
Dana D. Phan, Peter Chin-Hong, Emil T. Lin, Pascale Anderle, Wolfgang Sadee, B. Joseph Guglielmo

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