Amides

Chemistry; Biosynthesis
New Amides Containing Selenium as Potent Leishmanicidal Agents Targeting Trypanothione Reductase
Two new series of 28 selenocyanate and diselenide derivatives containing amide moieties were designed, synthesized, and evaluated for their leishmanicidal activity against Leishmania infantum axenic amastigotes, and selectivity was assessed in human THP-1 cells. Eleven compounds exhibited excellent leishmanicidal activity with EC₅₀ values lower than the...

Mikel Etxebeste-Mitxeltorena, Daniel Plano, Socorro Espuelas, Esther Moreno, Carlos Aydillo, Antonio Jiménez-Ruiz, Juan Carlos García Soriano, Carmen Sanmartín
Antiviral Agents
Extinction of West Nile Virus by Favipiravir through Lethal Mutagenesis
Estela Escribano-Romero, Nereida Jiménez de Oya, Esteban Domingo, Juan Carlos Saiz
Free

Antiviral Agents
Favipiravir Pharmacokinetics in Nonhuman Primates and Insights for Future Efficacy Studies of Hemorrhagic Fever Viruses
Vincent Madelain, Jérémie Guedj, France Mentré, Thi Huyen Tram Nguyen, Frédéric Jacquot, Lisa Oestereich, Takumi Kadota, Koichi Yamada, Anne-Marie Taburet, Xavier de Lamballerie, Hervé Raoul
Free

Antiviral Agents
In Vitro Antiviral Activity of Favipiravir (T-705) against Drug-Resistant Influenza and 2009 A(H1N1) Viruses
Katrina Sleeman, Vasiliy P. Mishin, Varough M. Deyde, Yousuke Furuta, Alexander I. Klimov, Larisa V. Gubareva
Antiviral Agents
Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice
Donald F. Smee, Brett L. Hurst, Min-Hui Wong, Kevin W. Bailey, E. Bart Tarbet, John D. Morrey, Yousuke Furuta
Antiviral Agents
Activity of T-705 in a Hamster Model of Yellow Fever Virus Infection in Comparison with That of a Chemically Related Compound, T-1106
Justin G. Julander, Kristiina Shafer, Donald F. Smee, John D. Morrey, Yousuke Furuta
Mechanisms of Resistance
Genetic Analysis of Fenhexamid-Resistant Field Isolates of the Phytopathogenic Fungus Botrytis cinerea
Sabine Fillinger, Pierre Leroux, Christiane Auclair, Christian Barreau, Charbel Al Hajj, Danièle Debieu
Antiviral Agents
In Vitro and In Vivo Activities of T-705 against Arenavirus and Bunyavirus Infections
Brian B. Gowen, Min-Hui Wong, Kie-Hoon Jung, Andrew B. Sanders, Michelle Mendenhall, Kevin W. Bailey, Yousuke Furuta, Robert W. Sidwell
Antiviral Agents
Activity of T-1106 in a Hamster Model of Yellow Fever Virus Infection
Justin G. Julander, Yousuke Furuta, Kristiina Shafer, Robert W. Sidwell
Antiviral Agents
Efficacy of Orally Administered T-705 on Lethal Avian Influenza A (H5N1) Virus Infections in Mice
Robert W. Sidwell, Dale L. Barnard, Craig W. Day, Donald F. Smee, Kevin W. Bailey, Min-Hui Wong, John D. Morrey, Yousuke Furuta

Main menu

User menu

Search

Amides

Pages