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Amidohydrolases

  • Open Access
    Susceptibility
    Pyrazinamide Susceptibility and pncA Mutation Profiles of Mycobacterium tuberculosis among Multidrug-Resistant Tuberculosis Patients in Bangladesh
    Arfatur Rahman, Sara Sabrina Ferdous, Shahriar Ahmed, S. M. Mazidur Rahman, Mohammad Khaja Mafij Uddin, Suporn Pholwat, Jean Gratz, Eric Houpt, Sayera Banu
  • LETTERS TO THE EDITOR
    Antimicrobial Activity of CHIR-090, an Inhibitor of Lipopolysaccharide Biosynthesis, against the Burkholderia cepacia Complex
    Karin Bodewits, Christian R. H. Raetz, John R. Govan, Dominic J. Campopiano
  • Mechanisms of Action: Physiological Effects
    Quorum-Quenching Acylase Reduces the Virulence of Pseudomonas aeruginosa in a Caenorhabditis elegans Infection Model
    Evelina Papaioannou, Mariana Wahjudi, Pol Nadal-Jimenez, Gudrun Koch, Rita Setroikromo, Wim J. Quax
  • Experimental Therapeutics
    In Vivo Characterization of the Peptide Deformylase Inhibitor LBM415 in Murine Infection Models
    Colin S. Osborne, Georg Neckermann, Evelin Fischer, Robert Pecanka, Donghui Yu, Kari Manni, Julie Goldovitz, Kerri Amaral, JoAnn Dzink-Fox, Neil S. Ryder
  • Mechanisms of Resistance
    Mutations in Three Distinct Loci Cause Resistance to Peptide Deformylase Inhibitors in Bacillus subtilis
    Yann Duroc, Carmela Giglione, Thierry Meinnel
  • Mechanisms of Resistance
    Pyrazinamide Resistance and pncA Gene Mutations in Mycobacterium tuberculosis
    Pontus Juréen, Jim Werngren, Juan-Carlos Toro, Sven Hoffner
  • Mechanisms of Resistance
    Reduced Susceptibility of Haemophilus influenzae to the Peptide Deformylase Inhibitor LBM415 Can Result from Target Protein Overexpression Due to Amplified Chromosomal def Gene Copy Number
    Charles R. Dean, Shubha Narayan, Joel Richards, Denis M. Daigle, Stacy Esterow, Jennifer A. Leeds, Heather Kamp, Xiaoling Puyang, Brigitte Wiedmann, Dieter Mueller, Hans Voshol, Jan van Oostrum, Daniel Wall, James Koehn, JoAnn Dzink-Fox, Neil S. Ryder
  • Erratum
    Characterization of pncA Mutations in Pyrazinamide-Resistant Mycobacterium tuberculosis in Brazil
    Vívian de F. Sumnienski Rodrigues, Maria Alice Telles, Marta Osório Ribeiro, Patrícia Izquierdo Cafrune, Maria Lucia Rosa Rossetti, Arnaldo Zaha
  • Susceptibility
    Peptide Deformylase Inhibitors as Potent Antimycobacterial Agents
    Jeanette W. P. Teo, Pamela Thayalan, David Beer, Amelia S. L. Yap, Mahesh Nanjundappa, Xinyi Ngew, Jeyaraj Duraiswamy, Sarah Liung, Veronique Dartois, Mark Schreiber, Samiul  Hasan, Michael Cynamon, Neil S. Ryder, Xia Yang, Beat Weidmann, Kathryn  Bracken, Thomas Dick, Kakoli Mukherjee
  • Mechanisms of Action: Physiological Effects
    Molecular Validation of LpxC as an Antibacterial Drug Target in Pseudomonas aeruginosa
    Khisimuzi E. Mdluli, Pamela R. Witte, Toni Kline, Adam W. Barb, Alice L. Erwin, Bryce E. Mansfield, Amanda L. McClerren, Michael C. Pirrung, L. Nathan Tumey, Paul Warrener, Christian R. H. Raetz, C. Kendall Stover

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