amikacin

Clinical Therapeutics
A Systematic Review of Single-Dose Aminoglycoside Therapy for Urinary Tract Infection: Is It Time To Resurrect an Old Strategy?
Increasing bacterial resistance and poor patient adherence rates limit the effectiveness of conventional antibiotic therapies for urinary tract infection (UTI). The objective of this study was to investigate whether a single aminoglycoside dose adequately treated UTI.

Kellie J. Goodlet, Fatima Z. Benhalima, Michael D. Nailor
Letter to the Editor
Emergence of Klebsiella pneumoniae Harboring the aac(6ʹ)-Ian Amikacin Resistance Gene
Paloma Troyano-Hernáez, Almudena Gutiérrez-Arroyo, Rosa Gómez-Gil, Jesús Mingorance, Fernando Lázaro-Perona
Pharmacology
Population Pharmacokinetics of Amikacin in Adult Patients with Cystic Fibrosis
Practitioners commonly use amikacin in patients with cystic fibrosis. Establishment of the pharmacokinetics of amikacin in adults with cystic fibrosis may increase the efficacy and safety of therapy.

Sílvia M. Illamola, Hoa Q. Huynh, Xiaoxi Liu, Zubin N. Bhakta, Catherine M. Sherwin, Theodore G. Liou, Holly Carveth, David C. Young
Clinical Therapeutics
Amikacin Inhalation as Salvage Therapy for Refractory Nontuberculous Mycobacterial Lung Disease
Byung Woo Jhun, Bumhee Yang, Seong Mi Moon, Hyun Lee, Hye Yun Park, Kyeongman Jeon, O Jung Kwon, Jungmin Ahn, Il Joon Moon, Sung Jae Shin, Charles L. Daley, Won-Jung Koh
Susceptibility
In Vitro Susceptibility of Mycobacterium tuberculosis to Amikacin, Kanamycin, and Capreomycin
J. A. Dijkstra, T. van der Laan, O. W. Akkerman, M. S. Bolhuis, W. C. M. de Lange, J. G. W. Kosterink, T. S. van der Werf, J. W. C. Alffenaar, D. van Soolingen
Pharmacology
Amikacin Pharmacokinetics To Optimize Dosing in Neonates with Perinatal Asphyxia Treated with Hypothermia
Sinziana Cristea, Anne Smits, Aida Kulo, Catherijne A. J. Knibbe, Mirjam van Weissenbruch, Elke H. J. Krekels, Karel Allegaert
Open Access

Mechanisms of Resistance
Antagonism between Front-Line Antibiotics Clarithromycin and Amikacin in the Treatment of Mycobacterium abscessus Infections Is Mediated by the whiB7 Gene
Mark Pryjma, Ján Burian, Kevin Kuchinski, Charles J. Thompson
Pharmacology
Penetration of Ciprofloxacin and Amikacin into the Alveolar Epithelial Lining Fluid of Rats with Pulmonary Fibrosis
Wentao Ni, Deqing Yang, Hekun Mei, Jin Zhao, Beibei Liang, Nan Bai, Dong Chai, Junchang Cui, Rui Wang, Youning Liu
Clinical Therapeutics
Reduced Chance of Hearing Loss Associated with Therapeutic Drug Monitoring of Aminoglycosides in the Treatment of Multidrug-Resistant Tuberculosis
R. van Altena, J. A. Dijkstra, M. E. van der Meer, J. F. Borjas Howard, J. G. W. Kosterink, D. van Soolingen, T. S. van der Werf, J. W. C. Alffenaar
Pharmacology
Optimization of Synergistic Combination Regimens against Carbapenem- and Aminoglycoside-Resistant Clinical Pseudomonas aeruginosa Isolates via Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling
Rajbharan Yadav, Jürgen B. Bulitta, Roger L. Nation, Cornelia B. Landersdorfer

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