amoebicidal effects

  • Application of Histone Deacetylase Inhibitors MPK472 and KSK64 as a Potential Treatment Option for <em>Acanthamoeba</em> Keratitis
    Experimental Therapeutics
    Application of Histone Deacetylase Inhibitors MPK472 and KSK64 as a Potential Treatment Option for Acanthamoeba Keratitis

    Treatment of Acanthamoeba keratitis (AK) is difficult because Acanthamoeba cysts are resistant to drugs, and as such, successful treatment requires an effective approach that inhibits cyst formation. Histone deacetylase inhibitors (HDACis) are involved in cell proliferation, differentiation, and apoptotic cell death. In this study, the effects of HDACis such as MPK472 and KSK64 on...

    Hae-Ahm Lee, So-Min Park, Ki-Back Chu, Fu-Shi Quan, Thomas Kurz, Marc Pflieger, Eun-Kyung Moon
Back to top