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ampicillin

  • Ampicillin and Ceftriaxone Solution Stability at Different Temperatures in Outpatient Parenteral Antimicrobial Therapy
    Clinical Therapeutics
    Ampicillin and Ceftriaxone Solution Stability at Different Temperatures in Outpatient Parenteral Antimicrobial Therapy

    The inclusion of ampicillin-containing regimens in outpatient parenteral antimicrobial therapy programs (OPAT) depends upon solution stability under conditions similar to those experienced in these programs. Lack of this information could hinder the inclusion in OPAT of patients suffering from Enterococcus faecalis infective endocarditis treated with ampicillin plus...

    L. Herrera-Hidalgo, L. E. López-Cortes, R. Luque-Márquez, J. Gálvez-Acebal, A. de Alarcón, L. F. López-Cortes, A. Gutiérrez-Valencia, M. V. Gil-Navarro
  • Meropenem versus Cefotaxime and Ampicillin as Empirical Antibiotic Treatment in Adult Bacterial Meningitis: a Quality Registry Study, 2008 to 2016
    Clinical Therapeutics
    Meropenem versus Cefotaxime and Ampicillin as Empirical Antibiotic Treatment in Adult Bacterial Meningitis: a Quality Registry Study, 2008 to 2016

    Cefotaxime, alone or with ampicillin, is frequently used in empirical treatment of acute bacterial meningitis (ABM). Meropenem is a less extensively investigated alternative. The aim of the study was to investigate the effects of empirical treatment with meropenem compared to cefotaxime plus ampicillin on outcome in ABM. The study was based on data from the Swedish quality register for ABM collected between January 2008 and December...

    Magnus Brink, Martin Glimåker, Jan Sjölin, Pontus Naucler
  • Free
    Treatment of Multidrug-Resistant Vancomycin-Resistant <span class="named-content genus-species" id="named-content-1">Enterococcus faecium</span> Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin
    Challenging Clinical Case in Antimicrobial Resistance
    Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin

    Weekly oritavancin plus ampicillin continuous infusion combination therapy was used to successfully treat a deep spine vancomycin-resistant Enterococcus faecium infection associated with hardware. Checkerboard and time-kill assays confirmed synergy between these two antibiotics.

    Samira Dahesh, Brian Wong, Victor Nizet, George Sakoulas, Truc T. Tran, Samuel L. Aitken
  • Prospective Observational Study of the Clinical Prognoses of Patients with Bloodstream Infections Caused by Ampicillin-Susceptible but Penicillin-Resistant <span class="named-content genus-species" id="named-content-1">Enterococcus faecalis</span>
    Editor's Pick Clinical Therapeutics
    Prospective Observational Study of the Clinical Prognoses of Patients with Bloodstream Infections Caused by Ampicillin-Susceptible but Penicillin-Resistant Enterococcus faecalis

    The purpose of this study was to evaluate the clinical impacts of ampicillin-susceptible but penicillin-resistant (ASPR) phenotypes of Enterococcus faecalis on clinical outcomes in patients with bloodstream infection (BSI). A total of 295 patients with an E. faecalis BSI from six sentinel hospitals...

    Dokyun Kim, Hyukmin Lee, Eun-Jeong Yoon, Jun Sung Hong, Jong Hee Shin, Young Uh, Kyeong Seob Shin, Jeong Hwan Shin, Young Ah Kim, Yoon Soo Park, Seok Hoon Jeong
  • Experimental Therapeutics
    Pharmacodynamics of Ceftaroline plus Ampicillin against Enterococcus faecalis in an In Vitro Pharmacokinetic/Pharmacodynamic Model of Simulated Endocardial Vegetations
    Brian J. Werth, Laura M. Shireman
  • Mechanisms of Resistance
    Differential Penicillin-Binding Protein 5 (PBP5) Levels in the Enterococcus faecium Clades with Different Levels of Ampicillin Resistance
    Maria Camila Montealegre, Jung Hyeob Roh, Meredith Rae, Milya G. Davlieva, Kavindra V. Singh, Yousif Shamoo, Barbara E. Murray
  • Clinical Therapeutics
    Pilot Study of Ampicillin-Ceftriaxone Combination for Treatment of Orthopedic Infections Due to Enterococcus faecalis
    G. Euba, J. Lora-Tamayo, O. Murillo, S. Pedrero, J. Cabo, R. Verdaguer, J. Ariza
  • Susceptibility
    Antimicrobial Activities of Piperacillin-Tazobactam against Haemophilus influenzae Isolates, Including β-Lactamase-Negative Ampicillin-Resistant and β-Lactamase-Positive Amoxicillin- Clavulanate-Resistant Isolates, and Mutations in Their Quinolone Resistance-Determining Regions
    Yoichi Hirakata, Kaori Ohmori, Miwako Mikuriya, Takeshi Saika, Kaoru Matsuzaki, Miyuki Hasegawa, Masumitsu Hatta, Natsuo Yamamoto, Hiroyuki Kunishima, Hisakazu Yano, Miho Kitagawa, Kazuaki Arai, Kazuyoshi Kawakami, Intetsu Kobayashi, Ronald N. Jones, Shigeru Kohno, Keizo Yamaguchi, Mitsuo Kaku
  • Mechanisms of Action: Physiological Effects
    P1A Recombinant β-Lactamase Prevents Emergence of Antimicrobial Resistance in Gut Microflora of Healthy Subjects during Intravenous Administration of Ampicillin
    Ann-Mari Tarkkanen, Tuula Heinonen, Rain Jõgi, Silja Mentula, Michel E. van der Rest, Curtis J. Donskey, Tuomas Kemppainen, Konstantin Gurbanov, Carl Erik Nord
  • Susceptibility
    Antibiotic Susceptibility of Invasive Haemophilus influenzae Strains in Canada
    Michelle L. Sill, Raymond S. W. Tsang

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