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antimalarial

  • Open Access
    Population Pharmacokinetics of Tafenoquine, a Novel Antimalarial
    Experimental Therapeutics
    Population Pharmacokinetics of Tafenoquine, a Novel Antimalarial

    Tafenoquine is a novel 8-aminoquinoline antimalarial drug recently approved by the U.S. Food and Drug Administration (FDA) for the radical cure of acute Plasmodium vivax malaria, which is the first new treatment in almost 60 years.

    Nilay Thakkar, Justin A. Green, Gavin C. K. W. Koh, Stephan Duparc, David Tenero, Navin Goyal
  • Experimental Therapeutics
    Prediction Model for Antimalarial Activities of Hemozoin Inhibitors by Using Physicochemical Properties
    Farhana Mosaddeque, Shusaku Mizukami, Mohamed Gomaa Kamel, Awet Alem Teklemichael, Truong Van Dat, Satoshi Mizuta, Dinh Van Toan, Ali Mahmoud Ahmed, Nguyen Lam Vuong, Mohamed Tamer Elhady, Hoang Thi Nam Giang, Tran Ngoc Dang, Michiko Fukuda, Lam K. Huynh, Yoshimasa Tanaka, Timothy J. Egan, Osamu Kaneko, Nguyen Tien Huy, Kenji Hirayama
  • Open Access
    Mechanisms of Action: Physiological Effects
    The Candidate Antimalarial Drug MMV665909 Causes Oxygen-Dependent mRNA Mistranslation and Synergizes with Quinoline-Derived Antimalarials
    Cindy Vallières, Simon V. Avery
  • Open Access
    Experimental Therapeutics
    Simplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based Drugs
    Bornface Gunsaru, Steven J. Burgess, Westin Morrill, Jane X. Kelly, Shawheen Shomloo, Martin J. Smilkstein, Katherine Liebman, David H. Peyton
  • Experimental Therapeutics
    High-Throughput Screening and Prediction Model Building for Novel Hemozoin Inhibitors Using Physicochemical Properties
    Nguyen Tien Huy, Pham Lan Chi, Jun Nagai, Tran Ngoc Dang, Evaristus Chibunna Mbanefo, Ali Mahmoud Ahmed, Nguyen Phuoc Long, Le Thi Bich Thoa, Le Phi Hung, Afaf Titouna, Kaeko Kamei, Hiroshi Ueda, Kenji Hirayama
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