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antimalarial drug resistance

  • Prevalence of <span class="named-content genus-species" id="named-content-1">Plasmodium falciparum</span> Kelch 13 (<em>PfK13</em>) and Ubiquitin-Specific Protease 1 (<em>pfubp1</em>) Gene Polymorphisms in Returning Travelers from Africa Reported in Eastern China
    Epidemiology and Surveillance
    Prevalence of Plasmodium falciparum Kelch 13 (PfK13) and Ubiquitin-Specific Protease 1 (pfubp1) Gene Polymorphisms in Returning Travelers from Africa Reported in Eastern China

    Delayed clearance of Plasmodium falciparum by artemisinin-based combination therapies (ACTs) has already been observed for African isolates. Here, we aimed to investigate the prevalence, among travelers returning from African countries, of polymorphisms in two genes correlated with delayed parasite clearance (encoding...

    He Yan, Xiangli Kong, Tao Zhang, Huihui Xiao, Xinyu Feng, Hong Tu, Jun Feng
  • Open Access
    <span class="named-content genus-species" id="named-content-1">Plasmodium falciparum</span> Kelch Propeller Polymorphisms in Clinical Isolates from Ghana from 2007 to 2016
    Epidemiology and Surveillance
    Plasmodium falciparum Kelch Propeller Polymorphisms in Clinical Isolates from Ghana from 2007 to 2016

    The continuous surveillance of polymorphisms in the kelch propeller domain of Plasmodium falciparum from Africa is important for the discovery of the actual markers of artemisinin resistance in the region. The information on the markers is crucial for control strategies involving chemotherapy and chemoprophylaxis for residents and nonimmune travelers to the country....

    Sena A. Matrevi, Philip Opoku-Agyeman, Neils B. Quashie, Selassie Bruku, Benjamin Abuaku, Kwadwo A. Koram, Anne Fox, Andrew Letizia, Nancy O. Duah-Quashie
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