Bacillus subtilis
Mechanisms of ResistanceBceAB-Type Antibiotic Resistance Transporters Appear To Act by Target Protection of Cell Wall SynthesisResistance against cell wall-active antimicrobial peptides in bacteria is often mediated by transporters. In low-GC-content Gram-positive bacteria, a common type of such transporters is BceAB-like systems, which frequently provide high-level resistance against peptide antibiotics that target intermediates of the lipid II cycle of cell wall synthesis. How a transporter can offer protection from drugs that are active on the cell surface,...
Mechanisms of Action: Physiological EffectsDaptomycin Pore Formation and Stoichiometry Depend on Membrane Potential of Target MembraneDaptomycin is a calcium-dependent lipodepsipeptide antibiotic clinically used to treat serious infections caused by Gram-positive pathogens. Its precise mode of action is somewhat controversial; the biggest issue is daptomycin pore formation, which we directly investigated here.
- Antiviral AgentsAnti-influenza Activity of a Bacillus subtilis Probiotic Strain
- Analytical ProceduresScreen for Inducers of Autolysis in Bacillus subtilis
- Mechanisms of Action: Physiological EffectsThe Large Mechanosensitive Channel MscL Determines Bacterial Susceptibility to the Bacteriocin Sublancin 168
- Mechanisms of Action: Physiological EffectsNovel Expression Vector for Secretion of Cecropin AD in Bacillus subtilis with Enhanced Antimicrobial Activity
- Mechanisms of Action: Physiological EffectsGenetic Analysis of Factors Affecting Susceptibility of Bacillus subtilis to Daptomycin
- Mechanisms of Action: Physiological EffectsDaptomycin versus Friulimicin B: In-Depth Profiling of Bacillus subtilis Cell Envelope Stress Responses