bacterial protein kinase
- Experimental TherapeuticsDeletion of pknG Abates Reactivation of Latent Mycobacterium tuberculosis in Mice
Eradication of tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), has been a challenge due to its uncanny ability to survive in a dormant state inside host granulomas for decades. Mtb rewires its metabolic and redox regulatory networks to survive in the hostile hypoxic and nutrient-limiting environment, facilitating the formation of drug-...