beta-lactams

Clinical Therapeutics
Incidence of Acute Kidney Injury among Patients Treated with Piperacillin-Tazobactam or Meropenem in Combination with Vancomycin
W. Cliff Rutter, David S. Burgess
Pharmacology
First Penicillin-Binding Protein Occupancy Patterns of β-Lactams and β-Lactamase Inhibitors in Klebsiella pneumoniae
Dhruvitkumar S. Sutaria, Bartolome Moya, Kari B. Green, Tae Hwan Kim, Xun Tao, Yuanyuan Jiao, Arnold Louie, George L. Drusano, Jürgen B. Bulitta
Pharmacology
Outcomes of Vancomycin plus a β-Lactam versus Vancomycin Only for Treatment of Methicillin-Resistant Staphylococcus aureus Bacteremia
James Truong, John J. Veillette, Steve C. Forland
Analytical Procedures
Development of a Novel Multipenicillin Assay and Assessment of the Impact of Analyte Degradation: Lessons for Scavenged Sampling in Antimicrobial Pharmacokinetic Study Design
Karin Kipper, Charlotte I. S. Barker, Joseph F. Standing, Mike Sharland, Atholl Johnston
Susceptibility
Multicenter Evaluation of Ceftazidime-Avibactam and Ceftolozane-Tazobactam Inhibitory Activity against Meropenem-Nonsusceptible Pseudomonas aeruginosa from Blood, Respiratory Tract, and Wounds
Mordechai Grupper, Christina Sutherland, David P. Nicolau
Experimental Therapeutics
Mycobacterium abscessus l,d-Transpeptidases Are Susceptible to Inactivation by Carbapenems and Cephalosporins but Not Penicillins
Pankaj Kumar, Varsha Chauhan, José Rogério A. Silva, Jerônimo Lameira, Felipe B. d'Andrea, Shao-Gang Li, Stephan L. Ginell, Joel S. Freundlich, Cláudio Nahum Alves, Scott Bailey, Keira A. Cohen, Gyanu Lamichhane
Mechanisms of Resistance
Tandem Amplification of the Staphylococcal Cassette Chromosome mec Element Can Drive High-Level Methicillin Resistance in Methicillin-Resistant Staphylococcus aureus
Laura A. Gallagher, Simone Coughlan, Nikki S. Black, Pierce Lalor, Elaine M. Waters, Bryan Wee, Mick Watson, Tim Downing, J. Ross Fitzgerald, Gerard T. A. Fleming, James P. O'Gara
Mechanisms of Resistance
Exploring the Landscape of Diazabicyclooctane (DBO) Inhibition: Avibactam Inactivation of PER-2 β-Lactamase
Melina Ruggiero, Krisztina M. Papp-Wallace, Magdalena A. Taracila, Maria F. Mojica, Christopher R. Bethel, Susan D. Rudin, Elise T. Zeiser, Gabriel Gutkind, Robert A. Bonomo, Pablo Power
Open Access

Experimental Therapeutics
Cyclic Boronates Inhibit All Classes of β-Lactamases
Samuel T. Cahill, Ricky Cain, David Y. Wang, Christopher T. Lohans, David W. Wareham, Henry P. Oswin, Jabril Mohammed, James Spencer, Colin W. G. Fishwick, Michael A. McDonough, Christopher J. Schofield, Jürgen Brem
Mechanisms of Resistance
Full-Genome Sequencing Identifies in the Genetic Background Several Determinants That Modulate the Resistance Phenotype in Methicillin-Resistant Staphylococcus aureus Strains Carrying the Novel mecC Gene
Catarina Milheiriço, Hermínia de Lencastre, Alexander Tomasz

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