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Blood Proteins

  • Pharmacology
    Assessment of Oritavancin Serum Protein Binding across Species
    Francis F. Arhin, Adam Belley, Geoffrey McKay, Sylvain Beaulieu, Ingrid Sarmiento, Thomas R. Parr, Gregory Moeck
  • Analytical Procedures
    Use of a Surface Plasmon Resonance Method To Investigate Antibiotic and Plasma Protein Interactions
    Françoise Banères-Roquet, Maxime Gualtieri, Philippe Villain-Guillot, Martine Pugnière, Jean-Paul Leonetti
  • Pharmacology
    Effect of Protein Binding on the Pharmacological Activity of Highly Bound Antibiotics
    Stephan Schmidt, Katharina Röck, Martina Sahre, Olaf Burkhardt, Martin Brunner, Maximilian T. Lobmeyer, Hartmut Derendorf
  • Experimental Therapeutics
    Role of Plasma Proteins in Pharmacokinetics of Micafungin, an Antifungal Antibiotic, in Analbuminemic Rats
    Fumie Abe, Jun Ueyama, Noriyo Kawasumi, Masayuki Nadai, Tamon Hayashi, Miki Kato, Masafumi Ohnishi, Hiroko Saito, Naoshi Takeyama, Takaaki Hasegawa
  • Experimental Therapeutics
    Protection of Mice from Lethal Escherichia coli Infection by Chimeric Human Bactericidal/Permeability-Increasing Protein and Immunoglobulin G1 Fc Gene Delivery
    Jindong Chen, Chengyao Li, Yuanzhi Guan, Qingli Kong, Chen Li, Xianghua Guo, Qinghua Chen, Xuefang Jing, Zhe Lv, Yunqing An
  • Mechanisms of Resistance
    Low-Level Resistance of Staphylococcus aureus to Thrombin-Induced Platelet Microbicidal Protein 1 In Vitro Associated with qacA Gene Carriage Is Independent of Multidrug Efflux Pump Activity
    A. S. Bayer, L. I. Kupferwasser, M. H. Brown, R. A. Skurray, S. Grkovic, T. Jones, K. Mukhopadhay, M. R. Yeaman
  • Mechanisms of Resistance
    Reduced Susceptibility of Staphylococcus aureus to Vancomycin and Platelet Microbicidal Protein Correlates with Defective Autolysis and Loss of Accessory Gene Regulator (agr) Function
    George Sakoulas, George M. Eliopoulos, Vance G. Fowler, Robert C. Moellering, Richard P. Novick, Natalie Lucindo, Michael R. Yeaman, Arnold S. Bayer
  • Susceptibility
    Activity of Cathelicidin Peptides against Chlamydia spp
    Manuela Donati, Korinne Di Leo, Monica Benincasa, Francesca Cavrini, Silvia Accardo, Alessandra Moroni, Renato Gennaro, Roberto Cevenini
  • Mechanisms of Action: Physiological Effects
    Platelet Microbicidal Protein 1: Structural Themes of a Multifunctional Antimicrobial Peptide
    Nannette Y. Yount, Kimberly D. Gank, Yan Qiong Xiong, Arnold S. Bayer, Thomas Pender, William H. Welch, Michael R. Yeaman
  • Pharmacology
    Safety, Pharmacokinetics, Pharmacodynamics, and Plasma Lipoprotein Distribution of Eritoran (E5564) during Continuous Intravenous Infusion into Healthy Volunteers
    Daniel P. Rossignol, Kishor M. Wasan, Eugene Choo, Edwin Yau, Nancy Wong, Jeffrey Rose, Jeffrey Moran, Melvyn Lynn

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