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cardiac surgery

  • Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections
    Pharmacology
    Antimicrobial Prophylaxis for Patients Undergoing Cardiac Surgery: Intraoperative Cefazolin Concentrations and Sternal Wound Infections

    This study characterizes the pharmacodynamics of antimicrobial prophylaxis and sternal wound infections following cardiac surgery. Duration of surgery and cefazolin plasma concentration during wound closure were independently associated with surgical site infection at 30 days.

    Sheryl A. Zelenitsky, Divna Calic, Rakesh C. Arora, Hilary P. Grocott, Ted M. Lakowski, Ryan Lillico, Robert E. Ariano
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