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clarithromycin

  • Species Distribution and Macrolide Susceptibility of <em>Mycobacterium fortuitum</em> Complex Clinical Isolates
    Mechanisms of Resistance
    Species Distribution and Macrolide Susceptibility of Mycobacterium fortuitum Complex Clinical Isolates

    The understanding of species distribution and inducible macrolide resistance in the Mycobacterium fortuitum complex (MFC) is limited. Of 90 mostly respiratory MFC clinical isolates, half were M. fortuitum, followed by M. peregrinum...

    Su-Young Kim, Seong Mi Moon, Byung Woo Jhun, O Jung Kwon, Hee Jae Huh, Nam Yong Lee, Seung Heon Lee, Sung Jae Shin, Shannon H. Kasperbauer, Gwen A. Huitt, Charles L. Daley, Won-Jung Koh
  • High-Dose Rifamycins Enable Shorter Oral Treatment in a Murine Model of <span class="named-content genus-species" id="named-content-1">Mycobacterium ulcerans</span> Disease
    Experimental Therapeutics
    High-Dose Rifamycins Enable Shorter Oral Treatment in a Murine Model of Mycobacterium ulcerans Disease

    Buruli ulcer (BU), caused by Mycobacterium ulcerans, is a neglected tropical skin and soft tissue infection that is associated with disability and social stigma. The mainstay of BU treatment is an 8-week course of rifampin (RIF) at 10 mg/kg of body weight and 150 mg/kg streptomycin (STR).

    Till F. Omansen, Deepak Almeida, Paul J. Converse, Si-Yang Li, Jin Lee, Ymkje Stienstra, Tjip van der Werf, Jacques H. Grosset, Eric L. Nuermberger
  • Emergence of Resistance to Macrolides and Rifampin in Clinical Isolates of <span class="named-content genus-species" id="named-content-1">Rhodococcus equi</span> from Foals in Central Kentucky, 1995 to 2017
    Epidemiology and Surveillance
    Emergence of Resistance to Macrolides and Rifampin in Clinical Isolates of Rhodococcus equi from Foals in Central Kentucky, 1995 to 2017

    The objective of this study was to determine the prevalence of Rhodococcus equi strains resistant to macrolides and rifampin over time in clinical samples from foals submitted to diagnostic laboratories in central Kentucky. We performed a retrospective observational study of all clinical samples from foals that were submitted to veterinary diagnostic laboratories in...

    Laura Huber, Steeve Giguère, Nathan M. Slovis, Craig N. Carter, Bonnie S. Barr, Noah D. Cohen, Justine Elam, Erdal Erol, Stephan J. Locke, Erica D. Phillips, Jacqueline L. Smith
  • Open Access
    Clinical Therapeutics
    Rifabutin Acts in Synergy and Is Bactericidal with Frontline Mycobacterium abscessus Antibiotics Clarithromycin and Tigecycline, Suggesting a Potent Treatment Combination
    Mark Pryjma, Ján Burian, Charles J. Thompson
  • Susceptibility
    Lipopeptide Paenipeptin Analogues Potentiate Clarithromycin and Rifampin against Carbapenem-Resistant Pathogens
    Sun Hee Moon, En Huang
  • Epidemiology and Surveillance
    Systematic Review, Meta-analysis, and Network Meta-analysis of the Cardiovascular Safety of Macrolides
    Einat Gorelik, Reem Masarwa, Amichai Perlman, Victoria Rotshild, Mordechai Muszkat, Ilan Matok
  • Open Access
    Clinical Therapeutics
    The Clarithromycin Susceptibility Genotype Affects the Treatment Outcome of Patients with Mycobacterium abscessus Lung Disease
    Qi Guo, Haiqing Chu, Meiping Ye, Zhemin Zhang, Bing Li, Shiyi Yang, Wei Ma, Fangyou Yu
  • Open Access
    Susceptibility
    Vancomycin and Clarithromycin Show Synergy against Mycobacterium abscessus In Vitro
    Devika Mukherjee, Mu-Lu Wu, Jeanette W. P. Teo, Thomas Dick
  • Open Access
    Mechanisms of Resistance
    Antagonism between Front-Line Antibiotics Clarithromycin and Amikacin in the Treatment of Mycobacterium abscessus Infections Is Mediated by the whiB7 Gene
    Mark Pryjma, Ján Burian, Kevin Kuchinski, Charles J. Thompson
  • Clinical Therapeutics
    A Randomized Controlled Trial Shows that both 14-Day Hybrid and Bismuth Quadruple Therapies Cure Most Patients with Helicobacter pylori Infection in Populations with Moderate Antibiotic Resistance
    Feng-Woei Tsay, Deng-Chyang Wu, Hsien-Chung Yu, Sung-Shuo Kao, Kung-Hung Lin, Jin-Shiung Cheng, Huay-Min Wang, Wen-Chi Chen, Wei-Chih Sun, Kuo-Wang Tsai, Ping-I Hsu

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