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DNA-Directed RNA Polymerases

  • Antiviral Agents
    Nucleotide Substrate Specificity of Anti-Hepatitis C Virus Nucleoside Analogs for Human Mitochondrial RNA Polymerase
    Maryam Ehteshami, Longhu Zhou, Sheida Amiralaei, Jadd R. Shelton, Jong Hyun Cho, Hongwang Zhang, Hao Li, Xiao Lu, Tugba Ozturk, Richard Stanton, Franck Amblard, Tamara R. McBrayer, Steven J. Coats, Raymond F. Schinazi
  • Mechanisms of Action: Physiological Effects
    Furanyl-Rhodanines Are Unattractive Drug Candidates for Development as Inhibitors of Bacterial RNA Polymerase
    Katherine R. Mariner, Rachel Trowbridge, Anil K. Agarwal, Keith Miller, Alex J. O'Neill, Colin W. G. Fishwick, Ian Chopra
  • Mechanisms of Resistance
    Involvement of the Beta Subunit of RNA Polymerase in Resistance to Streptolydigin and Streptovaricin in the Producer Organisms Streptomyces lydicus and Streptomyces spectabilis
    Marina Sánchez-Hidalgo, Luz Elena Núñez, Carmen Méndez, José A. Salas
  • Mechanisms of Resistance
    Contribution of rpoB2 RNA Polymerase β Subunit Gene to Rifampin Resistance in Nocardia Species
    Jun Ishikawa, Kazuhiro Chiba, Haruyo Kurita, Hiroyuki Satoh
  • LETTERS TO THE EDITOR
    Mutation in the Bacillus subtilis RNA Polymerase β′ Subunit Confers Resistance to Lipiarmycin
    Maxime Gualtieri, Philippe Villain-Guillot, Jaqueline Latouche, Jean-Paul Leonetti, Lionel Bastide
  • Mechanisms of Resistance
    Molecular Genetic and Structural Modeling Studies of Staphylococcus aureus RNA Polymerase and the Fitness of Rifampin Resistance Genotypes in Relation to Clinical Prevalence
    A. J. O'Neill, T. Huovinen, C. W. G. Fishwick, I. Chopra
  • Mechanisms of Resistance
    Frequency of Spontaneous Mutations That Confer Antibiotic Resistance in Chlamydia spp
    Rachel Binet, Anthony T. Maurelli
  • Mechanisms of Resistance
    Detection of rpoB Mutations Associated with Rifampin Resistance in Mycobacterium tuberculosis Using Denaturing Gradient Gel Electrophoresis
    Mark T. McCammon, John S. Gillette, Derek P. Thomas, Srinivas V. Ramaswamy, Edward A. Graviss, Barry N. Kreiswirth, Jan Vijg, Teresa N. Quitugua
  • Mechanisms of Resistance
    New Mutations and Horizontal Transfer of rpoB among Rifampin-Resistant Streptococcus pneumoniae from Four Spanish Hospitals
    María José Ferrándiz, Carmen Ardanuy, Josefina Liñares, José María García-Arenzana, Emilia Cercenado, Ana Fleites, Adela G. de la Campa
    and the Spanish Pneumococcal Infection Study Network
  • Mechanisms of Action: Physiological Effects
    Different Rifampin Sensitivities of Escherichia coli and Mycobacterium tuberculosis RNA Polymerases Are Not Explained by the Difference in the β-Subunit Rifampin Regions I and II
    N. Zenkin, A. Kulbachinskiy, I. Bass, V. Nikiforov

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