DNA Topoisomerases, Type II

Mechanisms of Resistance
Molecular Evolution Perspectives on Intraspecific Lateral DNA Transfer of Topoisomerase and Gyrase Loci in Streptococcus pneumoniae, with Implications for Fluoroquinolone Resistance Development and Spread
Michael J. Stanhope, Stacey L. Walsh, Julie A. Becker, Michael J. Italia, Karen A. Ingraham, Michael N. Gwynn, Tom Mathie, James A. Poupard, Linda A. Miller, James R. Brown, Heather Amrine-Madsen
Mechanisms of Resistance
Interspecies Recombination in Type II Topoisomerase Genes Is Not a Major Cause of Fluoroquinolone Resistance in Invasive Streptococcus pneumoniae Isolates in the United States
Mathias W. R. Pletz, Lesley McGee, Bernard Beall, Cynthia G. Whitney, Keith P. Klugman
Mechanisms of Resistance
Resistance Genes of Aminocoumarin Producers: Two Type II Topoisomerase Genes Confer Resistance against Coumermycin A₁ and Clorobiocin
Elisabeth Schmutz, Agnes Mühlenweg, Shu-Ming Li, Lutz Heide
Mechanisms of Action: Physiological Effects
Importance of the Fourth Alpha-Helix within the CAP Homology Domain of Type II Topoisomerase for DNA Cleavage Site Recognition and Quinolone Action
Dirk Strumberg, John L. Nitiss, Jiaowang Dong, Jerrylaine Walker, Marc C. Nicklaus, Kurt W. Kohn, Jonathan G. Heddle, Anthony Maxwell, Siegfried Seeber, Yves Pommier
Mechanisms of Resistance
Topoisomerase II and IV Quinolone Resistance-Determining Regions in Stenotrophomonas maltophilia Clinical Isolates with Different Levels of Quinolone Susceptibility
Sylvia Valdezate, Ana Vindel, Aurora Echeita, Fernando Baquero, Rafael Cantó
Mechanisms of Resistance
Type II Topoisomerase Quinolone Resistance-Determining Regions of Aeromonas caviae, A. hydrophila, and A. sobria Complexes and Mutations Associated with Quinolone Resistance
Marisol Goñi-Urriza, Corinne Arpin, Michèle Capdepuy, Véronique Dubois, Pierre Caumette, Claudine Quentin
Mechanisms of Resistance
Cleavable-Complex Formation by Wild-Type and Quinolone-Resistant Streptococcus pneumoniae Type II Topoisomerases Mediated by Gemifloxacin and Other Fluoroquinolones
Genoveva Yague, Julia E. Morris, Xiao-Su Pan, Katherine A. Gould, L. Mark Fisher
Susceptibility
Prevalence of Single Mutations in Topoisomerase Type II Genes among Levofloxacin-Susceptible Clinical Strains of Streptococcus pneumoniae Isolated in the United States in 1992 to 1996 and 1999 to 2000
Todd A. Davies, Alan Evangelista, Sharon Pfleger, Karen Bush, Daniel F. Sahm, Raul Goldschmidt
Mechanisms of Resistance
Type II Topoisomerase Mutations in Fluoroquinolone-Resistant Clinical Strains of Pseudomonas aeruginosa Isolated in 1998 and 1999: Role of Target Enzyme in Mechanism of Fluoroquinolone Resistance
Takaaki Akasaka, Mayumi Tanaka, Akihito Yamaguchi, Kenichi Sato
Mechanisms of Resistance
Resistance to Moxifloxacin in ToxigenicClostridium difficile Isolates Is Associated with Mutations in gyrA
Grit Ackermann, Yajarayma J. Tang, Robert Kueper, Peter Heisig, Arne C. Rodloff, Joseph Silva, Stuart H. Cohen

Pages