Fluorenes

Epidemiology and Surveillance
K13 Propeller Alleles, mdr1 Polymorphism, and Drug Effectiveness at Day 3 after Artemether-Lumefantrine Treatment for Plasmodium falciparum Malaria in Colombia, 2014-2015
Madeline Montenegro, Aaron T. Neal, Maritza Posada, Briegel De las Salas, Tatiana M. Lopera-Mesa, Rick M. Fairhurst, Alberto Tobon-Castaño
Antiviral Agents
Pharmacokinetic Interactions between Simeprevir and Ledipasvir in Treatment-Naive Hepatitis C Virus Genotype 1-Infected Patients without Cirrhosis Treated with a Simeprevir-Sofosbuvir-Ledipasvir Regimen
Stefan Bourgeois, Yves Horsmans, Frederik Nevens, Hans van Vlierberghe, Christophe Moreno, Maria Beumont, Leen Vijgen, Veerle van Eygen, Donghan Luo, Vera Hillewaert, Pieter Van Remoortere, Jolanda van de Logt, Sivi Ouwerkerk-Mahadevan
Open Access

Pharmacology
Bioavailability of Lumefantrine Is Significantly Enhanced with a Novel Formulation Approach, an Outcome from a Randomized, Open-Label Pharmacokinetic Study in Healthy Volunteers
Jay Prakash Jain, F. Joel Leong, Lan Chen, Sampath Kalluri, Vishal Koradia, Daniel S. Stein, Marie-Christine Wolf, Gangadhar Sunkara, Jagannath Kota
Open Access

Clinical Therapeutics
pfk13-Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom
Colin J. Sutherland, Paul Lansdell, Mandy Sanders, Julian Muwanguzi, Donelly A. van Schalkwyk, Harparkash Kaur, Debbie Nolder, Julie Tucker, Hayley M. Bennett, Thomas D. Otto, Matthew Berriman, Trupti A. Patel, Roderick Lynn, Effrossyni Gkrania-Klotsas, Peter L. Chiodini
Pharmacology
Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine during Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania
Sofia Friberg Hietala, Andreas Mårtensson, Billy Ngasala, Sabina Dahlström, Niklas Lindegårdh, Anna Annerberg, Zul Premji, Anna Färnert, Pedro Gil, Anders Björkman, Michael Ashton
Mechanisms of Resistance
Selection of Known Plasmodium falciparum Resistance-Mediating Polymorphisms by Artemether-Lumefantrine and Amodiaquine- Sulfadoxine-Pyrimethamine but Not Dihydroartemisinin- Piperaquine in Burkina Faso
Anyirékun Fabrice Somé, Yves Y. Séré, Christian Dokomajilar, Issaka Zongo, Noël Rouamba, Bryan Greenhouse, Jean-Bosco Ouédraogo, Philip J. Rosenthal
Pharmacology
Pharmacokinetics of Artemether-Lumefantrine and Artesunate-Amodiaquine in Children in Kampala, Uganda
Julia Mwesigwa, Sunil Parikh, Bryan McGee, Polina German, Troy Drysdale, Joan N. Kalyango, Tamara D. Clark, Grant Dorsey, Niklas Lindegardh, Anna Annerberg, Philip J. Rosenthal, Moses R. Kamya, Francesca Aweeka
Pharmacology
Population Pharmacokinetics of Lumefantrine in Pregnant Women Treated with Artemether-Lumefantrine for Uncomplicated Plasmodium falciparum Malaria
Joel Tarning, Rose McGready, Niklas Lindegardh, Elizabeth A. Ashley, Mupawjay Pimanpanarak, Benjamas Kamanikom, Anna Annerberg, Nicholas P. J. Day, Kasia Stepniewska, Pratap Singhasivanon, Nicholas J. White, François Nosten
Mechanisms of Resistance
Selection of Plasmodium falciparum Multidrug Resistance Gene 1 Alleles in Asexual Stages and Gametocytes by Artemether-Lumefantrine in Nigerian Children with Uncomplicated Falciparum Malaria
C. T. Happi, G. O. Gbotosho, O. A. Folarin, A. Sowunmi, T. Hudson, M. O'Neil, W. Milhous, D. F. Wirth, A. M. J. Oduola
Mechanisms of Resistance
Amodiaquine and Artemether-Lumefantrine Select Distinct Alleles of the Plasmodium falciparum mdr1 Gene in Tanzanian Children Treated for Uncomplicated Malaria
G. S. Humphreys, I. Merinopoulos, J. Ahmed, C. J. M. Whitty, T. K. Mutabingwa, C. J. Sutherland, R. L. Hallett

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