Fungal Proteins

Open Access

Mechanisms of Resistance
The Gastrointestinal Tract Is a Major Source of Echinocandin Drug Resistance in a Murine Model of Candida glabrata Colonization and Systemic Dissemination
Kelley R. Healey, Yoji Nagasaki, Matthew Zimmerman, Milena Kordalewska, Steven Park, Yanan Zhao, David S. Perlin
Susceptibility
Single-Center Evaluation of an Agar-Based Screening for Azole Resistance in Aspergillus fumigatus by Using VIPcheck
J. B. Buil, H. A. L. van der Lee, A. J. M. M. Rijs, J. Zoll, J. A. M. F. Hovestadt, W. J. G. Melchers, P. E. Verweij
Open Access

Mechanisms of Resistance
Emergence of Echinocandin Resistance Due to a Point Mutation in the fks1 Gene of Aspergillus fumigatus in a Patient with Chronic Pulmonary Aspergillosis
Cristina Jiménez-Ortigosa, Caroline Moore, David W. Denning, David S. Perlin
Mechanisms of Resistance
Development and Validation of a High-Resolution Melting Assay To Detect Azole Resistance in Aspergillus fumigatus
L. Bernal-Martínez, H. Gil, O. Rivero-Menéndez, S. Gago, M. Cuenca-Estrella, E. Mellado, A. Alastruey-Izquierdo
Mechanisms of Resistance
Mediator Tail Module Is Required for Tac1-Activated CDR1 Expression and Azole Resistance in Candida albicans
Zhongle Liu, Lawrence C. Myers
Mechanisms of Resistance
De Novo Acquisition of Resistance to SCY-078 in Candida glabrata Involves FKS Mutations That both Overlap and Are Distinct from Those Conferring Echinocandin Resistance
Cristina Jiménez-Ortigosa, Winder B. Perez, David Angulo, Katyna Borroto-Esoda, David S. Perlin
Mechanisms of Resistance
Drug Sensitivity and Resistance Mechanism in Aspergillus Section Nigri Strains from Japan
Aki Hashimoto, Daisuke Hagiwara, Akira Watanabe, Maki Yahiro, Alimu Yikelamu, Takashi Yaguchi, Katsuhiko Kamei
Free

Challenging Clinical Case in Antimicrobial Resistance
Progressive Dispersion of Azole Resistance in Aspergillus fumigatus: Fatal Invasive Aspergillosis in a Patient with Acute Myeloid Leukemia Infected with an A. fumigatus Strain with a cyp51A TR₄₆ Y121F M172I T289A Allele
Susann Rößler, Oliver Bader, Friedrich Stölzel, Ulrich Sommer, Birgit Spiess, Stephan Geibel, Dieter Buchheidt, Uwe Groß, Gustavo Baretton, Enno Jacobs, Luis Ostrosky-Zeichner
Open Access

Mechanisms of Resistance
ERG11 Gene Mutations and MDR1 Upregulation Confer Pan-Azole Resistance in Candida tropicalis Causing Disseminated Candidiasis in an Acute Lymphoblastic Leukemia Patient on Posaconazole Prophylaxis
Liangshun You, Wenbin Qian, Qing Yang, Liping Mao, Li Zhu, Xianbo Huang, Jie Jin, Haitao Meng
Mechanisms of Resistance
Contributions of both ATP-Binding Cassette Transporter and Cyp51A Proteins Are Essential for Azole Resistance in Aspergillus fumigatus
Sanjoy Paul, Daniel Diekema, W. Scott Moye-Rowley

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