fungi
SusceptibilityIn Vitro and In Vivo Study on the Synergistic Effect of Minocycline and Azoles against Pathogenic FungiIn vitro and in vivo interactions of minocycline and azoles, including itraconazole, voriconazole, and posaconazole, against filamentous pathogenic fungi were investigated. A total of 56 clinical isolates were studied in vitro via broth microdilution checkerboard technique, including 20 strains of Aspergillus fumigatus, 7 strains of...
Clinical TherapeuticsDisparate Candida albicans Biofilm Formation in Clinical Lipid Emulsions Due to Capric Acid-Mediated InhibitionReceipt of parenteral nutrition (PN) remains an independent risk factor for developing catheter-related bloodstream infections (CR-BSI) caused by fungi, including by the polymorphic fungus Candida albicans, which is notoriously adept at forming drug-resistant biofilm structures. Among a variety of macronutrients, PN solutions contain lipid emulsions to supply daily...
- Experimental TherapeuticsAcylhydrazones as Antifungal Agents Targeting the Synthesis of Fungal Sphingolipids
- Letter to the EditorSynergy between Pyrvinium Pamoate and Azoles against Exophiala dermatitidis
- Mechanisms of Action: Physiological EffectsFludioxonil Induces Drk1, a Fungal Group III Hybrid Histidine Kinase, To Dephosphorylate Its Downstream Target, Ypd1