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gallium

  • Iron/Heme Metabolism-Targeted Gallium(III) Nanoparticles Are Active against Extracellular and Intracellular <em>Pseudomonas aeruginosa</em> and <em>Acinetobacter baumannii</em>
    Experimental Therapeutics
    Iron/Heme Metabolism-Targeted Gallium(III) Nanoparticles Are Active against Extracellular and Intracellular Pseudomonas aeruginosa and Acinetobacter baumannii

    Iron/heme acquisition systems are critical for microorganisms to acquire iron from the human host, where iron sources are limited due to the nutritional immune system and insolubility of the ferric form of iron. Prior work has shown that a variety of gallium compounds can interfere with bacterial iron acquisition.

    Seoung-ryoung Choi, Bradley E. Britigan, Prabagaran Narayanasamy
  • Experimental Therapeutics
    A Topical Hydrogel with Deferiprone and Gallium-Protoporphyrin Targets Bacterial Iron Metabolism and Has Antibiofilm Activity
    Katharina Richter, Nicky Thomas, Jolien Claeys, Jonathan McGuane, Clive A. Prestidge, Tom Coenye, Peter-John Wormald, Sarah Vreugde
  • Open Access
    Antiviral Agents
    Ga(III) Nanoparticles Inhibit Growth of both Mycobacterium tuberculosis and HIV and Release of Interleukin-6 (IL-6) and IL-8 in Coinfected Macrophages
    Seoung-ryoung Choi, Bradley E. Britigan, Prabagaran Narayanasamy
  • Mechanisms of Action: Physiological Effects
    Acinetobacter baumannii Biofilm Formation in Human Serum and Disruption by Gallium
    Federica Runci, Carlo Bonchi, Emanuela Frangipani, Daniela Visaggio, Paolo Visca
  • Experimental Therapeutics
    Gallium Disrupts Iron Uptake by Intracellular and Extracellular Francisella Strains and Exhibits Therapeutic Efficacy in a Murine Pulmonary Infection Model
    Oyebode Olakanmi, John S. Gunn, Shengchang Su, Shilpa Soni, Daniel J. Hassett, Bradley E. Britigan
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