Genome, Bacterial

Open Access

Mechanisms of Resistance
Whole-Transcriptome and -Genome Analysis of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates Identifies Downregulation of ethA as a Mechanism of Ethionamide Resistance
Lynne de Welzen, Vegard Eldholm, Kashmeel Maharaj, Abigail L. Manson, Ashlee M. Earl, Alexander S. Pym
Open Access

Epidemiology and Surveillance
First Detailed Genetic Characterization of the Structural Organization of Type III Arginine Catabolic Mobile Elements Harbored by Staphylococcus epidermidis by Using Whole-Genome Sequencing
Brenda A. McManus, Aoife M. O'Connor, Peter M. Kinnevey, Michael O'Sullivan, Ioannis Polyzois, David C. Coleman
Epidemiology and Surveillance
Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains
Hajime Kanamori, Christian M. Parobek, Jonathan J. Juliano, James R. Johnson, Brian D. Johnston, Timothy J. Johnson, David J. Weber, William A. Rutala, Deverick J. Anderson
Mechanisms of Resistance
Influence of IS256 on Genome Variability and Formation of Small-Colony Variants in Staphylococcus aureus
Franziska Kleinert, René Kallies, Michael Hort, Annegret Zweynert, Christiane Szekat, Michael Nagel, Gabriele Bierbaum
Epidemiology and Surveillance
A Clostridium difficile Lineage Endemic to Costa Rican Hospitals Is Multidrug Resistant by Acquisition of Chromosomal Mutations and Novel Mobile Genetic Elements
Gabriel Ramírez-Vargas, Carlos Quesada-Gómez, Luis Acuña-Amador, Diana López-Ureña, Tatiana Murillo, María del Mar Gamboa-Coronado, Esteban Chaves-Olarte, Nicholas Thomson, Evelyn Rodríguez-Cavallini, César Rodríguez
Mechanisms of Resistance
Functional Characterization of the DNA Gyrases in Fluoroquinolone-Resistant Mutants of Francisella novicida
Yvan Caspar, Claire Siebert, Vivien Sutera, Corinne Villers, Alexandra Aubry, Claudine Mayer, Max Maurin, Patricia Renesto
Open Access

Epidemiology and Surveillance
A Whole-Genome Sequencing Approach To Study Cefoxitin-Resistant Salmonella enterica Serovar Heidelberg Isolates from Various Sources
Romaine Edirmanasinghe, Rita Finley, E. Jane Parmley, Brent P. Avery, Carolee Carson, Sadjia Bekal, George Golding, Michael R. Mulvey
Mechanisms of Resistance
Full-Genome Sequencing Identifies in the Genetic Background Several Determinants That Modulate the Resistance Phenotype in Methicillin-Resistant Staphylococcus aureus Strains Carrying the Novel mecC Gene
Catarina Milheiriço, Hermínia de Lencastre, Alexander Tomasz
Epidemiology and Surveillance
Protracted Regional Dissemination of GIM-1-Producing Serratia marcescens in Western Germany
Andreas F. Wendel, Martin Kaase, Ingo B. Autenrieth, Silke Peter, Philipp Oberhettinger, Heime Rieber, Klaus Pfeffer, Colin R. MacKenzie, Matthias Willmann
Mechanisms of Resistance
Emergence of Ceftazidime-Avibactam Resistance Due to Plasmid-Borne bla_KPC-3 Mutations during Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infections
Ryan K. Shields, Liang Chen, Shaoji Cheng, Kalyan D. Chavda, Ellen G. Press, Avin Snyder, Ruchi Pandey, Yohei Doi, Barry N. Kreiswirth, M. Hong Nguyen, Cornelius J. Clancy

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