glomerular filtration rate
- PharmacologyReappraisal of Linezolid Dosing in Renal Impairment To Improve Safety
Linezolid is administered as a fixed dose to all patients despite evidence of increased exposure and myelosuppression in renal impairment. The objectives of these studies were to assess the risk of thrombocytopenia with standard-dose linezolid in renal impairment and to identify an alternate dosing strategy.