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HIV infections

  • Utility of Targeted, Amplicon-Based Deep Sequencing To Detect Resistance to First-Line Tuberculosis Drugs in Botswana
    Analytical Procedures
    Utility of Targeted, Amplicon-Based Deep Sequencing To Detect Resistance to First-Line Tuberculosis Drugs in Botswana

    Multidrug-resistant tuberculosis (TB) is an alarming threat, and targeted deep sequencing (DS) may be an effective method for rapid identification of drug-resistant profiles, including detection of heteroresistance. We evaluated the sensitivity and specificity of targeted DS versus phenotypic drug susceptibility testing (pDST) among patients starting first-line anti-TB therapy in Botswana. Overall, we found high concordance between DS...

    Qiao Wang, Chawangwa Modongo, Christopher Allender, David M. Engelthaler, Robin M. Warren, Nicola M. Zetola, Sanghyuk S. Shin
  • Antiviral Agents
    Effects of Maraviroc versus Efavirenz in Combination with Zidovudine-Lamivudine on the CD4/CD8 Ratio in Treatment-Naive HIV-Infected Individuals
    Sergio Serrano-Villar, Giorgia Caruana, Alexander Zlotnik, José A. Pérez-Molina, Santiago Moreno
  • Antiviral Agents
    Genetics of Nevirapine Metabolic Pathways at Steady State in HIV-Infected Cambodians
    Philippine Eloy, Adrien Tessier, Patty Fan-Havard, Monidarin Chou, Céline Verstuyft, Anne-Marie Taburet, David W. Haas, Julie Bertrand
    and the ANRS12154 Study Group
  • Antiviral Agents
    Evaluation of the Innate Immune Modulator Acitretin as a Strategy To Clear the HIV Reservoir
    Edurne Garcia-Vidal, Marc Castellví, Maria Pujantell, Roger Badia, Antoni Jou, Lucia Gomez, Teresa Puig, Bonaventura Clotet, Ester Ballana, Eva Riveira-Muñoz, José A. Esté
  • Open Access
    Antiviral Agents
    Effect of Rifampin on the Single-Dose Pharmacokinetics of Oral Cabotegravir in Healthy Subjects
    S. L. Ford, K. Sutton, Y. Lou, Z. Zhang, A. Tenorio, C. Trezza, P. Patel, W. Spreen
  • Antiviral Agents
    Potent Inhibition of HIV-1 Replication in Resting CD4 T Cells by Resveratrol and Pterostilbene
    Chi N. Chan, Benjamin Trinité, David N. Levy
  • Antiviral Agents
    MK-8591 (4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine) Exhibits Potent Activity against HIV-2 Isolates and Drug-Resistant HIV-2 Mutants in Culture
    Vincent H. Wu, Robert A. Smith, Sara Masoum, Dana N. Raugi, Selly Ba, Moussa Seydi, Jay A. Grobler, Geoffrey S. Gottlieb
    and for the University of Washington–Dakar HIV-2 Study Group
  • Antiviral Agents
    A Lower Baseline CD4/CD8 T-Cell Ratio Is Independently Associated with Immunodiscordant Response to Antiretroviral Therapy in HIV-Infected Subjects
    I. Rosado-Sánchez, I. Herrero-Fernández, A. I. Álvarez-Ríos, M. Genebat, M. A. Abad-Carrillo, E. Ruiz-Mateos, F. Pulido, J. González-García, M. Montero, E. Bernal-Morell, F. Vidal, M. Leal, Y. M. Pacheco
  • Antiviral Agents
    The Myxobacterial Metabolite Soraphen A Inhibits HIV-1 by Reducing Virus Production and Altering Virion Composition
    Eric Fleta-Soriano, Katarína Smutná, Javier P. Martínez, Cristina Lorca Oró, S. Kashif Sadiq, Gilles Mirambeau, Carmen Lopez-Iglesias, Marta Bosch, Albert Pol, Mark Brönstrup, Juana Diez, Andreas Meyerhans
  • Antiviral Agents
    Impact of HIV-1 Integrase L74F and V75I Mutations in a Clinical Isolate on Resistance to Second-Generation Integrase Strand Transfer Inhibitors
    Atsuko Hachiya, Karen A. Kirby, Yoko Ido, Urara Shigemi, Masakazu Matsuda, Reiko Okazaki, Junji Imamura, Stefan G. Sarafianos, Yoshiyuki Yokomaku, Yasumasa Iwatani

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