HIV Reverse Transcriptase

Antiviral Agents
Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase, RNase H, and Integrase Activities by Hydroxytropolones
Joël Didierjean, Catherine Isel, Flore Querré, Jean-François Mouscadet, Anne-Marie Aubertin, Jean-Yves Valnot, Serge R. Piettre, Roland Marquet
Antiviral Agents
Anti-Human Immunodeficiency Virus Type 1 Activity of the Nonnucleoside Reverse Transcriptase Inhibitor GW678248 in Combination with Other Antiretrovirals against Clinical Isolate Viruses and In Vitro Selection for Resistance
Richard J. Hazen, Robert J. Harvey, Marty H. St. Clair, Robert G. Ferris, George A. Freeman, Jeffrey H. Tidwell, Lee T. Schaller, Jill R. Cowan, Steven A. Short, Karen R. Romines, Joseph H. Chan, Lawrence R. Boone
Antiviral Agents
High Potency of Indolyl Aryl Sulfone Nonnucleoside Inhibitors towards Drug-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutants Is Due to Selective Targeting of Different Mechanistic Forms of the Enzyme
Reynel Cancio, Romano Silvestri, Rino Ragno, Marino Artico, Gabriella De Martino, Giuseppe La Regina, Emmanuele Crespan, Samantha Zanoli, Ulrich Hübscher, Silvio Spadari, Giovanni Maga
Antiviral Agents
Newly Designed Six-Membered Azasugar Nucleotide-Containing Phosphorothioate Oligonucleotides as Potent Human Immunodeficiency Virus Type 1 Inhibitors
Dong-Seong Lee, Kyeong-Eun Jung, Cheol-Hee Yoon, Hong Lim, Yong-Soo Bae
Antiviral Agents
Analysis of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Subunit Structure/Function in the Context of Infectious Virions and Human Target Cells
Alok Mulky, John C. Kappes
Antiviral Agents
Quantifying Mixed Populations of Drug-Resistant Human Immunodeficiency Virus Type 1
Michael J. Moser, Meta Ruckstuhl, Christine A. Larsen, Amanda J. Swearingen, Miroslaw Kozlowski, Leda Bassit, Prem L. Sharma, Raymond F. Schinazi, James R. Prudent
Minireview
Insertions in the Human Immunodeficiency Virus Type 1 Protease and Reverse Transcriptase Genes: Clinical Impact and Molecular Mechanisms
Mark A. Winters, Thomas C. Merigan
Antiviral Agents
The L74V Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Counteracts Enhanced Excision of Zidovudine Monophosphate Associated with Thymidine Analog Resistance Mutations
Luis R. Miranda, Matthias Götte, Daniel R. Kuritzkes
Antiviral Agents
Impaired Rescue of Chain-Terminated DNA Synthesis Associated with the L74V Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase
Fernando A. Frankel, Bruno Marchand, Dan Turner, Matthias Götte, Mark A. Wainberg
Antiviral Agents
Intracellular Substrates for the Primer-Unblocking Reaction by Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Detection and Quantitation in Extracts from Quiescent- and Activated-Lymphocyte Subpopulations
Anthony J. Smith, Peter R. Meyer, Deshratn Asthana, Margarita R. Ashman, Walter A. Scott

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