Hydroxamic Acids

Open Access

Experimental Therapeutics
Reducing Antibacterial Development Risk for GSK1322322 by Exploring Potential Human Dose Regimens in Nonclinical Efficacy Studies Using Immunocompetent Rats
Jennifer L. Hoover, Christine M. Singley, Philippa Elefante, Peter DeMarsh, Magdalena Zalacain, Stephen Rittenhouse
Susceptibility
In Vitro and In Vivo Efficacy of an LpxC Inhibitor, CHIR-090, Alone or Combined with Colistin against Pseudomonas aeruginosa Biofilm
Jun Hou Tan, Celine Vidaillac, Joey Kuok Hoong Yam, Song Lin Chua, Michael Givskov, Liang Yang
LETTERS TO THE EDITOR
Antimicrobial Activity of CHIR-090, an Inhibitor of Lipopolysaccharide Biosynthesis, against the Burkholderia cepacia Complex
Karin Bodewits, Christian R. H. Raetz, John R. Govan, Dominic J. Campopiano
Mechanisms of Action: Physiological Effects
Desketoneoenactin-Siderophore Conjugates for Candida: Evidence of Iron Transport-Dependent Species Selectivity
Geneviève Bernier, Vinay Girijavallabhan, Aaron Murray, Noormohamed Niyaz, Pingyu Ding, Marvin J. Miller, François Malouin
Mechanisms of Resistance
Pharmacokinetics in Animals and Humans of a First-in-Class Peptide Deformylase Inhibitor
Sandhya Ramanathan-Girish, Juliet McColm, John M. Clements, Phil Taupin, Sue Barrowcliffe, John Hevizi, Sharon Safrin, Clive Moore, Gary Patou, Heinz Moser, Alison Gadd, Ute Hoch, Vernon Jiang, Denene Lofland, Kirk W. Johnson
Letter to the Editor
Antimalarial and Antileishmanial Activities of Aroyl-Pyrrolyl-Hydroxyamides, a New Class of Histone Deacetylase Inhibitors
Antonello Mai, Ilaria Cerbara, Sergio Valente, Silvio Massa, Larry A. Walker, Babu L. Tekwani
Mechanisms of Action: Physiological Effects
Peptide Deformylase Inhibitors as Antibacterial Agents: Identification of VRC3375, a Proline-3-Alkylsuccinyl Hydroxamate Derivative, by Using an Integrated Combinatorial and Medicinal Chemistry Approach
D. Chen, C. Hackbarth, Z. J. Ni, C. Wu, W. Wang, R. Jain, Y. He, K. Bracken, B. Weidmann, D. V. Patel, J. Trias, R. J. White, Z. Yuan
Experimental Therapeutics
Efficacy of BB-83698, a Novel Peptide Deformylase Inhibitor, in a Mouse Model of Pneumococcal Pneumonia
E. Azoulay-Dupuis, J. Mohler, J. P. Bédos
Mechanisms of Action: Physiological Effects
Subinhibitory Concentrations of the Deformylase Inhibitor Actinonin Increase Bacterial Release of Neutrophil-Activating Peptides: a New Approach to Antimicrobial Chemotherapy
Huamei Fu, Claes Dahlgren, Johan Bylund
Mechanisms of Action: Physiological Effects
N-Alkyl Urea Hydroxamic Acids as a New Class of Peptide Deformylase Inhibitors with Antibacterial Activity
Corinne J. Hackbarth, Dawn Z. Chen, Jason G. Lewis, Kirk Clark, James B. Mangold, Jeffrey A. Cramer, Peter S. Margolis, Wen Wang, Jim Koehn, Charlotte Wu, S. Lopez, George Withers, Helen Gu, Elina Dunn, R. Kulathila, Shi-Hao Pan, Wilma L. Porter, Jeff Jacobs, Joaquim Trias, Dinesh V. Patel, Beat Weidmann, Richard J. White, Zhengyu Yuan

Main menu

User menu

Search

Hydroxamic Acids

Pages