Hygromycin B

Chemistry; Biosynthesis
The Final Step of Hygromycin A Biosynthesis, Oxidation of C-5″-Dihydrohygromycin A, Is Linked to a Putative Proton Gradient-Dependent Efflux
Vidya Dhote, Agata L. Starosta, Daniel N. Wilson, Kevin A. Reynolds
Mechanisms of Resistance
An O-Phosphotransferase Catalyzes Phosphorylation of Hygromycin A in the Antibiotic-Producing Organism Streptomyces hygroscopicus
Vidya Dhote, Shuchi Gupta, Kevin A. Reynolds
Susceptibility
In Vitro Antibacterial Activity of CE-156811, a Novel Analog Derived from Hygromycin A
Gregory G. Stone, Dennis Girard, Steve Finegan, Joan Duignan, John Schafer, Meghan Maloney, Richard P. Zaniewski, Steven J. Brickner, Sarah K. Wade, Phuong T. Le, Michael D. Huband
Mechanisms of Action: Physiological Effects
Hygromycin B Inhibition of Protein Synthesis and Ribosome Biogenesis in Escherichia coli
Susan M. McGaha, W. Scott Champney
Chemistry; Biosynthesis
Biosynthetic Origin of Hygromycin A
El-Sayed E. Habib, J. Neel Scarsdale, Kevin A. Reynolds
Mechanisms of Resistance
Role of 16S rRNA Helix 44 in Ribosomal Resistance to Hygromycin B
P. Pfister, M. Risch, D. E. Brodersen, E. C. Böttger
Mechanisms of Action: Physiological Effects
A Ribosomal ATPase Is a Target for Hygromycin B Inhibition on Escherichia coli Ribosomes
M. Clelia Ganoza, Michael C. Kiel

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