integrons

Mechanisms of Resistance
First Occurrence of the OXA-198 Carbapenemase in Enterobacterales
A carbapenem-resistant Citrobacter sp. was recovered from routine screening of multidrug-resistant bacteria. This isolate coproduced OXA-48 and OXA-198. OXA-48 was carried by the prototypical IncL plasmid, whereas OXA-198 was carried by a peculiar IncHI-type plasmid. This carbapenemase gene was inserted within a class 1 integron located on a conjugative plasmid. This report describes the first occurrence of OXA-198 in ...

Rémy A. Bonnin, Agnès B. Jousset, Lauraine Gauthier, Cécile Emeraud, Delphine Girlich, Aimie Sauvadet, Garance Cotellon, Thomas Jové, Laurent Dortet, Thierry Naas
Mechanisms of Resistance
Integron-Derived Aminoglycoside-Sensing Riboswitches Control Aminoglycoside Acetyltransferase Resistance Gene Expression
Class 1 integrons accumulate antibiotic resistance genes by site-specific recombination at aatI-1 sites. Captured genes are transcribed from a promoter located within the integron; for class 1 integrons, the first gene to be transcribed and translated normally encodes an aminoglycoside antibiotic resistance protein (either an acetyltransferase [AAC] or adenyltransferase [AAD]).

Shasha Wang, Weizhi He, Wenxia Sun, Jun Zhang, Yaowen Chang, Dongrong Chen, Alastair I. H. Murchie
Mechanisms of Resistance
PGI2 Is a Novel SGI1-Relative Multidrug-Resistant Genomic Island Characterized in Proteus mirabilis
Chang-Wei Lei, Yan-Peng Chen, Ling-Han Kong, Jin-Xin Zeng, Yong-Xiang Wang, An-Yun Zhang, Hong-Ning Wang
Open Access

Mechanisms of Resistance
pSTM6-275, a Conjugative IncHI2 Plasmid of Salmonella enterica That Confers Antibiotic and Heavy-Metal Resistance under Changing Physiological Conditions
Helen Billman-Jacobe, Yuhong Liu, Ruth Haites, Tom Weaver, Lily Robinson, Marc Marenda, Mike Dyall-Smith
Mechanisms of Resistance
Expression of the aac(6′)-Ib-cr Gene in Class 1 Integrons
Sophie Raherison, Thomas Jove, Margaux Gaschet, Emilie Pinault, Aurore Tabesse, Carmen Torres, Marie-Cécile Ploy
Mechanisms of Resistance
Integron-Associated DfrB4, a Previously Uncharacterized Member of the Trimethoprim-Resistant Dihydrofolate Reductase B Family, Is a Clinically Identified Emergent Source of Antibiotic Resistance
Jacynthe L. Toulouse, Thaddeus J. Edens, Lorea Alejaldre, Amee R. Manges, Joelle N. Pelletier
Mechanisms of Resistance
Complete Nucleotide Sequences of Two VIM-1-Encoding Plasmids from Klebsiella pneumoniae and Leclercia adecarboxylata Isolates of Czech Origin
Ivo Papousek, Costas C. Papagiannitsis, Matej Medvecky, Jaroslav Hrabak, Monika Dolejska
Mechanisms of Resistance
attI1-Located Small Open Reading Frames ORF-17 and ORF-11 in a Class 1 Integron Affect Expression of a Gene Cassette Possessing a Canonical Shine-Dalgarno Sequence
Costas C. Papagiannitsis, Leonidas S. Tzouvelekis, Eva Tzelepi, Vivi Miriagou
Mechanisms of Resistance
qnrVC-Like Gene Located in a Novel Complex Class 1 Integron Harboring the ISCR1 Element in an Aeromonas punctata Strain from an Aquatic Environment in Shandong Province, China
Ruirui Xia, Xianhu Guo, Yuzhen Zhang, Hai Xu
Mechanisms of Resistance
Characterization of DIM-1, an Integron-Encoded Metallo-β-Lactamase from a Pseudomonas stutzeri Clinical Isolate in the Netherlands
Laurent Poirel, Jose-Manuel Rodríguez-Martínez, Nashwan Al Naiemi, Yvette J. Debets-Ossenkopp, Patrice Nordmann

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