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Isoquinolines

  • Antiviral Agents
    A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase
    Karen A. Kirby, Nataliya A. Myshakina, Martin T. Christen, Yue-Lei Chen, Hilary A. Schmidt, Andrew D. Huber, Zhaoyong Xi, Seongmi Kim, Rohit K. Rao, Skyler T. Kramer, Qiongying Yang, Kamalendra Singh, Michael A. Parniak, Zhengqiang Wang, Rieko Ishima, Stefan G. Sarafianos
  • Pharmacology
    Activity of Sanguinarine against Candida albicans Biofilms
    Hua Zhong, Dan-Dan Hu, Gan-Hai Hu, Juan Su, Shuang Bi, Zhuo-Er Zhang, Zheng Wang, Ri-Li Zhang, Zheng Xu, Yuan-Ying Jiang, Yan Wang
  • Susceptibility
    Activity of Indenoisoquinolines against African Trypanosomes
    Rahul P. Bakshi, Dongpei Sang, Andrew Morrell, Mark Cushman, Theresa A. Shapiro
  • Mechanisms of Action: Physiological Effects
    Activities of Naphthylisoquinoline Alkaloids and Synthetic Analogs against Leishmania major
    Alicia Ponte-Sucre, Johan H. Faber, Tanja Gulder, Inga Kajahn, Sarah E. H. Pedersen, Martina Schultheis, Gerhard Bringmann, Heidrun Moll
  • Susceptibility
    Ligands of the Peripheral Benzodiazepine Receptor Are Potent Inhibitors of Plasmodium falciparum and Toxoplasma gondii In Vitro
    Florence Dzierszinski, Alexandra Coppin, Marlene Mortuaire, Etienne Dewailly, Christian Slomianny, Jean-Claude Ameisen, Frederic DeBels, Stanislas Tomavo
  • Antiviral Agents
    GF120918, a P-Glycoprotein Modulator, Increases the Concentration of Unbound Amprenavir in the Central Nervous System in Rats
    Jeffrey E. Edwards, Kenneth R. Brouwer, Patrick J. McNamara
  • Susceptibility
    In Vitro Activities of Two Antimitotic Compounds, Pancratistatin and 7-Deoxynarciclasine, againstEncephalitozoon intestinalis, a Microsporidium Causing Infections in Humans
    Meryem Ouarzane-Amara, Jean-François Franetich, Dominique Mazier, George R. Pettit, Laurent Meijer, Christian Doerig, Isabelle Desportes-Livage
  • Antiviral Agents
    Antiviral Properties of a Series of 1,6-Naphthyridine and 7,8-Dihydroisoquinoline Derivatives Exhibiting Potent Activity against Human Cytomegalovirus
    Jean Bedard, Suzanne May, Lucille L'Heureux, Thomas Stamminger, Alice Copsey, John Drach, John Huffman, Laval Chan, Haolun Jin, Robert F. Rando
  • Pharmacology
    Analysis of the Pharmacokinetic Interaction between Cephalexin and Quinapril by a Nonlinear Mixed-Effect Model
    C. Padoin, M. Tod, G. Perret, O. Petitjean
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