k13 gene

  • Evolution and Genetic Diversity of the <em>k13</em> Gene Associated with Artemisinin Delayed Parasite Clearance in <span class="named-content genus-species" id="named-content-1">Plasmodium falciparum</span>
    Epidemiology and Surveillance
    Evolution and Genetic Diversity of the k13 Gene Associated with Artemisinin Delayed Parasite Clearance in Plasmodium falciparum

    Mutations in the Plasmodium falciparum k13 (Pfk13) gene are linked to delayed parasite clearance in response to artemisinin-based combination therapies (ACTs) in Southeast Asia. To explore the evolutionary rate and constraints acting on this gene, k13 orthologs from species sharing a recent common ancestor with...

    M. Andreína Pacheco, Esha R. Kadakia, Zainab Chaudhary, Douglas J. Perkins, Julia Kelley, Shashidhar Ravishankar, Michael Cranfield, Eldin Talundzic, Venkatachalam Udhayakumar, Ananias A. Escalante
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