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kidney transplantation

  • Intravenous Immunoglobulin Administration Significantly Increases BKPyV Genotype-Specific Neutralizing Antibody Titers in Kidney Transplant Recipients
    Antiviral Agents
    Intravenous Immunoglobulin Administration Significantly Increases BKPyV Genotype-Specific Neutralizing Antibody Titers in Kidney Transplant Recipients

    BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) is one of the major causes of kidney graft dysfunction, and there are no BKPyV-specific antiviral therapies available. BKPyV neutralizing antibodies (NAbs) play key roles in protecting against BKPyV replication and represent a potential therapeutic or preventive strategy. In this study, we evaluated NAb titers in intravenous immunoglobulin (i.v. Ig) preparations and in kidney...

    Aurélie Velay, Morgane Solis, Ilies Benotmane, Pierre Gantner, Eric Soulier, Bruno Moulin, Sophie Caillard, Samira Fafi-Kremer
  • Antiviral Agents
    Pharmacokinetics and Exposure-Response Analysis of RG7667, a Combination of Two Anticytomegalovirus Monoclonal Antibodies, in a Phase 2a Randomized Trial To Prevent Cytomegalovirus Infection in High-Risk Kidney Transplant Recipients
    Rong Deng, Yehong Wang, Mauricio Maia, Tracy Burgess, Jacqueline M. McBride, X. Charlene Liao, Jorge A. Tavel, William D. Hanley
  • Antiviral Agents
    Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial of RG7667, a Combination Monoclonal Antibody, for Prevention of Cytomegalovirus Infection in High-Risk Kidney Transplant Recipients
    Julie H. Ishida, Anita Patel, Aneesh K. Mehta, Philippe Gatault, Jacqueline M. McBride, Tracy Burgess, Michael A. Derby, David R. Snydman, Brinda Emu, Becket Feierbach, Ashley E. Fouts, Mauricio Maia, Rong Deng, Carrie M. Rosenberger, Lynn A. Gennaro, Natalee S. Striano, X. Charlene Liao, Jorge A. Tavel
  • Susceptibility
    Escherichia coli Sequence Type ST131 as an Emerging Fluoroquinolone-Resistant Uropathogen among Renal Transplant Recipients
    James R. Johnson, Brian Johnston, Connie Clabots, Michael A. Kuskowski, Swaroop Pendyala, Chitrita DebRoy, Bogdan Nowicki, James Rice
  • Antiviral Agents
    Early Selection of a New UL97 Mutant with a Severe Defect of Ganciclovir Phosphorylation after Valaciclovir Prophylaxis and Short-Term Ganciclovir Therapy in a Renal Transplant Recipient
    Sébastien Hantz, Detlef Michel, Anne-Marie Fillet, Vincent Guigonis, Gaël Champier, Marie-Christine Mazeron, Albert Bensman, François Denis, Thomas Mertens, Axelle Dehee, Sophie Alain
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