Klebsiella pneumoniae

Open Access

Pharmacology
Evaluation of Activity and Emergence of Resistance of Polymyxin B and ZTI-01 (Fosfomycin for Injection) against KPC-Producing Klebsiella pneumoniae
John K. Diep, Rajnikant Sharma, Evelyn J. Ellis-Grosse, Cely S. Abboud, Gauri G. Rao
Experimental Therapeutics
Combating Multidrug-Resistant Pathogens with Host-Directed Nonantibiotic Therapeutics
Jourdan A. Andersson, Jian Sha, Michelle L. Kirtley, Emily Reyes, Eric C. Fitts, Sara M. Dann, Ashok K. Chopra
Epidemiology and Surveillance
Concentration and Variety of Carbapenemase Producers in Recreational Coastal Waters Showing Distinct Levels of Pollution
Raphael P. Paschoal, Eloiza H. Campana, Laís L. Corrêa, Lara F. Montezzi, Lina R. L. Barrueto, Isadora R. da Silva, Raquel R. Bonelli, Laura de S. Castro, Renata C. Picão
Open Access

Mechanisms of Resistance
Meropenem-Vaborbactam Resistance Selection, Resistance Prevention, and Molecular Mechanisms in Mutants of KPC-Producing Klebsiella pneumoniae
Dongxu Sun, Debora Rubio-Aparicio, Kirk Nelson, Michael N. Dudley, Olga Lomovskaya
Experimental Therapeutics
Inhibition of Fosfomycin Resistance Protein FosA by Phosphonoformate (Foscarnet) in Multidrug-Resistant Gram-Negative Pathogens
Ryota Ito, Adam D. Tomich, Christi L. McElheny, Roberta T. Mettus, Nicolas Sluis-Cremer, Yohei Doi
Pharmacology
Pharmacokinetics-Pharmacodynamics of Tazobactam in Combination with Cefepime in an In Vitro Infection Model
Brian D. VanScoy, David Tenero, Simon Turner, David M. Livermore, Jennifer McCauley, Haley Conde, Sujata M. Bhavnani, Christopher M. Rubino, Paul G. Ambrose
Mechanisms of Resistance
High-Level Resistance to Colistin Mediated by Various Mutations in the crrB Gene among Carbapenemase-Producing Klebsiella pneumoniae
Aurélie Jayol, Patrice Nordmann, Adrian Brink, Maria-Virginia Villegas, Véronique Dubois, Laurent Poirel
Mechanisms of Resistance
Structure and Dynamics of FosA-Mediated Fosfomycin Resistance in Klebsiella pneumoniae and Escherichia coli
Erik H. Klontz, Adam D. Tomich, Sebastian Günther, Justin A. Lemkul, Daniel Deredge, Zach Silverstein, JoAnna F. Shaw, Christi McElheny, Yohei Doi, Patrick L. Wintrode, Alexander D. MacKerell, Nicolas Sluis-Cremer, Eric J. Sundberg
Mechanisms of Resistance
Translocation of Carbapenemase Gene bla_KPC-2 both Internal and External to Transposons Occurs via Novel Structures of Tn1721 and Exhibits Distinct Movement Patterns
Yu Tang, Gang Li, Wei Liang, Pinghua Shen, Ying Zhang, Xiaofei Jiang
Clinical Therapeutics
Population Pharmacokinetics of High-Dose Continuous-Infusion Meropenem and Considerations for Use in the Treatment of Infections Due to KPC-Producing Klebsiella pneumoniae
Piergiorgio Cojutti, Assunta Sartor, Elda Righi, Claudio Scarparo, Matteo Bassetti, Federico Pea

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Klebsiella pneumoniae

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