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Leishmania donovani

  • Experimental Therapeutics
    Nanotized Curcumin and Miltefosine, a Potential Combination for Treatment of Experimental Visceral Leishmaniasis
    Brajendra Tiwari, Richa Pahuja, Pradeep Kumar, Srikanta Kumar Rath, Kailash Chand Gupta, Neena Goyal
  • Mechanisms of Action: Physiological Effects
    Snapshot Profiling of the Antileishmanial Potency of Lead Compounds and Drug Candidates against Intracellular Leishmania donovani Amastigotes, with a Focus on Human-Derived Host Cells
    Markela Koniordou, Stephen Patterson, Susan Wyllie, Karin Seifert
  • Experimental Therapeutics
    Antileishmanial and Antitrypanosomal Activities of the 8-Aminoquinoline Tafenoquine
    Vanessa Yardley, Francisco Gamarro, Simon L. Croft
  • Susceptibility
    In Vitro Susceptibilities of Leishmania donovani Promastigote and Amastigote Stages to Antileishmanial Reference Drugs: Practical Relevance of Stage-Specific Differences
    Marieke Vermeersch, Raquel Inocêncio da Luz, Kim Toté, Jean-Pierre Timmermans, Paul Cos, Louis Maes
  • Mechanisms of Resistance
    Topoisomerase I Gene Mutations at F270 in the Large Subunit and N184 in the Small Subunit Contribute to the Resistance Mechanism of the Unicellular Parasite Leishmania donovani towards 3,3′-Diindolylmethane
    Amit Roy, Somdeb BoseDasgupta, Agneyo Ganguly, Parasuraman Jaisankar, Hemanta K. Majumder
  • Susceptibility
    In Vitro Susceptibility of Field Isolates of Leishmania donovani to Miltefosine and Amphotericin B: Correlation with Sodium Antimony Gluconate Susceptibility and Implications for Treatment in Areas of Endemicity
    Dhiraj Kumar, Arpita Kulshrestha, Ruchi Singh, Poonam Salotra
  • Susceptibility
    Antiparasitic Activities and Toxicities of Individual Enantiomers of the 8-Aminoquinoline 8-[(4-Amino-1-Methylbutyl)Amino]-6-Methoxy-4-Methyl-5-[3,4-Dichlorophenoxy]Quinoline Succinate
    N. P. Dhammika Nanayakkara, Arba L. Ager, Marilyn S. Bartlett, Vanessa Yardley, Simon L. Croft, Ikhlas A. Khan, James D. McChesney, Larry A. Walker
  • Mechanisms of Resistance
    Inhibition of ABC Transporters Abolishes Antimony Resistance in Leishmania Infection
    Jayati Mookerjee Basu, Ananda Mookerjee, Rajdeep Banerjee, Manik Saha, Subhankar Singh, Ksudiram Naskar, Gayetri Tripathy, Prabhat K. Sinha, Krishna Pandey, Shyam Sundar, Sanjeev Bimal, Pradip K. Das, Soumitra K. Choudhuri, Syamal Roy
  • Mechanisms of Action: Physiological Effects
    Modulation of Gene Expression in Human Macrophages Treated with the Anti-Leishmania Pentavalent Antimonial Drug Sodium Stibogluconate
    Karima El Fadili, Michaël Imbeault, Nadine Messier, Gaétan Roy, Benjamin Gourbal, Marc Bergeron, Michel J. Tremblay, Danielle Légaré, Marc Ouellette
  • Experimental Therapeutics
    Oral Therapy with Amlodipine and Lacidipine, 1,4-Dihydropyridine Derivatives Showing Activity against Experimental Visceral Leishmaniasis
    Partha Palit, Nahid Ali

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