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Leishmania donovani

  • Susceptibility
    Antileishmanial Structure-Activity Relationships of Synthetic Phospholipids: In Vitro and In Vivo Activities of Selected Derivatives
    Karin Seifert, Andreas Lemke, Simon L. Croft, Oliver Kayser
  • Mechanisms of Action: Physiological Effects
    Miltefosine (Hexadecylphosphocholine) Inhibits Cytochrome c Oxidase in Leishmania donovani Promastigotes
    Juan Román Luque-Ortega, Luis Rivas
  • Mechanisms of Action: Physiological Effects
    Miltefosine Affects Lipid Metabolism in Leishmania donovani Promastigotes
    M. Rakotomanga, S. Blanc, K. Gaudin, P. Chaminade, P. M. Loiseau
  • Mechanisms of Action: Physiological Effects
    Leishmania donovani Polyamine Biosynthetic Enzyme Overproducers as Tools To Investigate the Mode of Action of Cytotoxic Polyamine Analogs
    Sigrid C. Roberts, Yuqui Jiang, Judith Gasteier, Benjamin Frydman, Laurence J. Marton, Olle Heby, Buddy Ullman
  • Mechanisms of Action: Physiological Effects
    Antileishmanial Effect of 3-Aminooxy-1-Aminopropane Is Due to Polyamine Depletion
    Sushma Singh, Angana Mukherjee, Alex R. Khomutov, Lo Persson, Olle Heby, Mitali Chatterjee, Rentala Madhubala
  • Susceptibility
    Interaction between Miltefosine and Amphotericin B: Consequences for Their Activities towards Intestinal Epithelial Cells and Leishmania donovani Promastigotes In Vitro
    Cécile  Ménez, Marion Buyse, Madeleine Besnard, Robert Farinotti, Philippe M. Loiseau, Gillian Barratt
  • Mechanisms of Action: Physiological Effects
    Sodium Antimony Gluconate Induces Generation of Reactive Oxygen Species and Nitric Oxide via Phosphoinositide 3-Kinase and Mitogen-Activated Protein Kinase Activation in Leishmania donovani-Infected Macrophages
    Jayati Mookerjee Basu, Ananda Mookerjee, Prosenjit Sen, Suniti Bhaumik, Pradip Sen, Subha Banerjee, Ksudiram Naskar, Soumitra K. Choudhuri, Bhaskar Saha, Sanghamitra Raha, Syamal Roy
  • Experimental Therapeutics
    Antitrypanosomal and Antileishmanial Activities of Flavonoids and Their Analogues: In Vitro, In Vivo, Structure-Activity Relationship, and Quantitative Structure-Activity Relationship Studies
    Deniz Tasdemir, Marcel Kaiser, Reto Brun, Vanessa Yardley, Thomas J. Schmidt, Fatma Tosun, Peter Rüedi
  • Experimental Therapeutics
    In Vitro and In Vivo Interactions between Miltefosine and Other Antileishmanial Drugs
    Karin Seifert, Simon L. Croft
  • Mechanisms of Resistance
    Resistance of Leishmania donovani to Sodium Stibogluconate Is Related to the Expression of Host and Parasite γ-Glutamylcysteine Synthetase
    K. C. Carter, S. Hutchison, F. L. Henriquez, D. Légaré, M. Ouellette, C. W. Roberts, A. B. Mullen

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