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Meglumine

  • Experimental Therapeutics
    Mixed Formulation of Conventional and Pegylated Meglumine Antimoniate-Containing Liposomes Reduces Inflammatory Process and Parasite Burden in Leishmania infantum-Infected BALB/c Mice
    Levi Eduardo Soares Reis, Rory Cristiane Fortes de Brito, Jamille Mirelle de Oliveira Cardoso, Fernando Augusto Siqueira Mathias, Rodrigo Dian Oliveira Aguiar Soares, Claudia Martins Carneiro, Paula Melo de Abreu Vieira, Guilherme Santos Ramos, Frédéric Jean Georges Frézard, Bruno Mendes Roatt, Alexandre Barbosa Reis
  • Mechanisms of Resistance
    Knockdown of Host Antioxidant Defense Genes Enhances the Effect of Glucantime on Intracellular Leishmania braziliensis in Human Macrophages
    Jair Téllez, Ibeth Romero, Maurilio José Soares, Mario Steindel, Alvaro José Romanha
  • Chemistry; Biosynthesis
    Library of Seleno-Compounds as Novel Agents against Leishmania Species
    Álvaro Martín-Montes, Daniel Plano, Rubén Martín-Escolano, Verónica Alcolea, Marta Díaz, Silvia Pérez-Silanes, Socorro Espuelas, Esther Moreno, Clotilde Marín, Ramón Gutiérrez-Sánchez, Carmen Sanmartín, Manuel Sánchez-Moreno
  • Experimental Therapeutics
    Meglumine Antimoniate (Glucantime) Causes Oxidative Stress-Derived DNA Damage in BALB/c Mice Infected by Leishmania (Leishmania) infantum
    Vanessa Ribeiro Moreira, Luís Cláudio Lima de Jesus, Rossy-Eric Pereira Soares, Luis Douglas Miranda Silva, Bruno Araújo Serra Pinto, Maria Norma Melo, Antonio Marcus de Andrade Paes, Silma Regina Ferreira Pereira
  • Experimental Therapeutics
    Comparative Efficacies of Two Antimony Regimens To Treat Leishmania braziliensis-Induced Cutaneous Leishmaniasis in Rhesus Macaques (Macaca mulatta)
    G. Grimaldi, R. Porrozzi, K. Friedrich, A. Teva, R. S. Marchevsky, F. Vieira, N. Miekeley, F. J. R. Paumgartten
  • Clinical Therapeutics
    Reduced Tissue Parasitic Load and Infectivity to Sand Flies in Dogs Naturally Infected by Leishmania (Leishmania) chagasi following Treatment with a Liposome Formulation of Meglumine Antimoniate
    Raul R. Ribeiro, Eliane P. Moura, Vitor M. Pimentel, Weverton M. Sampaio, Sydnei M. Silva, Dante A. Schettini, Cintia F. Alves, Ferdinan A. Melo, Wagner L. Tafuri, Cynthia Demicheli, Maria N. Melo, Frédéric Frézard, Marilene S. M. Michalick
  • Pharmacology
    Oral Delivery of Meglumine Antimoniate-β-Cyclodextrin Complex for Treatment of Leishmaniasis
    Cynthia Demicheli, Rosemary Ochoa, José B. B. da Silva, Camila A. B. Falcão, Bartira Rossi-Bergmann, Alan L. de Melo, Ruben D. Sinisterra, Frédéric Frézard
  • Chemistry; Biosynthesis
    Glutathione-Induced Conversion of Pentavalent Antimony to Trivalent Antimony in Meglumine Antimoniate
    Frédéric Frézard, Cynthia Demicheli, Claúdio S. Ferreira, Michelle A. P. Costa
  • Mechanisms of Resistance
    Stage-Specific Activity of Pentavalent Antimony against Leishmania donovani Axenic Amastigotes
    Moshe Ephros, Ari Bitnun, Pninit Shaked, Ella Waldman, Dan Zilberstein
  • Mechanisms of Resistance
    Sensitivity of Leishmania viannia panamensis to Pentavalent Antimony Is Correlated with the Formation of Cleavable DNA-Protein Complexes
    Armando Lucumi, Sara Robledo, Vivian Gama, Nancy G. Saravia

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