Meglumine

Experimental Therapeutics
Mixed Formulation of Conventional and Pegylated Meglumine Antimoniate-Containing Liposomes Reduces Inflammatory Process and Parasite Burden in Leishmania infantum-Infected BALB/c Mice
Levi Eduardo Soares Reis, Rory Cristiane Fortes de Brito, Jamille Mirelle de Oliveira Cardoso, Fernando Augusto Siqueira Mathias, Rodrigo Dian Oliveira Aguiar Soares, Claudia Martins Carneiro, Paula Melo de Abreu Vieira, Guilherme Santos Ramos, Frédéric Jean Georges Frézard, Bruno Mendes Roatt, Alexandre Barbosa Reis
Mechanisms of Resistance
Knockdown of Host Antioxidant Defense Genes Enhances the Effect of Glucantime on Intracellular Leishmania braziliensis in Human Macrophages
Jair Téllez, Ibeth Romero, Maurilio José Soares, Mario Steindel, Alvaro José Romanha
Chemistry; Biosynthesis
Library of Seleno-Compounds as Novel Agents against Leishmania Species
Álvaro Martín-Montes, Daniel Plano, Rubén Martín-Escolano, Verónica Alcolea, Marta Díaz, Silvia Pérez-Silanes, Socorro Espuelas, Esther Moreno, Clotilde Marín, Ramón Gutiérrez-Sánchez, Carmen Sanmartín, Manuel Sánchez-Moreno
Experimental Therapeutics
Meglumine Antimoniate (Glucantime) Causes Oxidative Stress-Derived DNA Damage in BALB/c Mice Infected by Leishmania (Leishmania) infantum
Vanessa Ribeiro Moreira, Luís Cláudio Lima de Jesus, Rossy-Eric Pereira Soares, Luis Douglas Miranda Silva, Bruno Araújo Serra Pinto, Maria Norma Melo, Antonio Marcus de Andrade Paes, Silma Regina Ferreira Pereira
Experimental Therapeutics
Comparative Efficacies of Two Antimony Regimens To Treat Leishmania braziliensis-Induced Cutaneous Leishmaniasis in Rhesus Macaques (Macaca mulatta)
G. Grimaldi, R. Porrozzi, K. Friedrich, A. Teva, R. S. Marchevsky, F. Vieira, N. Miekeley, F. J. R. Paumgartten
Clinical Therapeutics
Reduced Tissue Parasitic Load and Infectivity to Sand Flies in Dogs Naturally Infected by Leishmania (Leishmania) chagasi following Treatment with a Liposome Formulation of Meglumine Antimoniate
Raul R. Ribeiro, Eliane P. Moura, Vitor M. Pimentel, Weverton M. Sampaio, Sydnei M. Silva, Dante A. Schettini, Cintia F. Alves, Ferdinan A. Melo, Wagner L. Tafuri, Cynthia Demicheli, Maria N. Melo, Frédéric Frézard, Marilene S. M. Michalick
Pharmacology
Oral Delivery of Meglumine Antimoniate-β-Cyclodextrin Complex for Treatment of Leishmaniasis
Cynthia Demicheli, Rosemary Ochoa, José B. B. da Silva, Camila A. B. Falcão, Bartira Rossi-Bergmann, Alan L. de Melo, Ruben D. Sinisterra, Frédéric Frézard
Chemistry; Biosynthesis
Glutathione-Induced Conversion of Pentavalent Antimony to Trivalent Antimony in Meglumine Antimoniate
Frédéric Frézard, Cynthia Demicheli, Claúdio S. Ferreira, Michelle A. P. Costa
Mechanisms of Resistance
Stage-Specific Activity of Pentavalent Antimony against Leishmania donovani Axenic Amastigotes
Moshe Ephros, Ari Bitnun, Pninit Shaked, Ella Waldman, Dan Zilberstein
Mechanisms of Resistance
Sensitivity of Leishmania viannia panamensis to Pentavalent Antimony Is Correlated with the Formation of Cleavable DNA-Protein Complexes
Armando Lucumi, Sara Robledo, Vivian Gama, Nancy G. Saravia

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