MurT-GatD

  • Role of MurT C-Terminal Domain in the Amidation of <span class="named-content genus-species" id="named-content-1">Staphylococcus aureus</span> Peptidoglycan
    Mechanisms of Resistance
    Role of MurT C-Terminal Domain in the Amidation of Staphylococcus aureus Peptidoglycan

    Glutamate amidation, a secondary modification of the peptidoglycan, was first identified in Staphylococcus aureus. It is catalyzed by the protein products of the murT and gatD genes, which are conserved and colocalized in the genomes of most sequenced Gram-positive bacterial species. The MurT-GatD complex is required for cell viability, full...

    Bárbara V. Gonçalves, Raquel Portela, Ricardo Lobo, Teresa A. Figueiredo, Inês R. Grilo, Ana Madalena Ludovice, Hermínia de Lencastre, Jorge S. Dias, Rita G. Sobral
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