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nitro compounds

  • Open Access
    Synergic Effect of Allopurinol in Combination with Nitroheterocyclic Compounds against <span class="named-content genus-species" id="named-content-1">Trypanosoma cruzi</span>
    Experimental Therapeutics
    Synergic Effect of Allopurinol in Combination with Nitroheterocyclic Compounds against Trypanosoma cruzi

    Combination therapy has gained attention as a possible strategy for overcoming the limitations of the present therapeutic arsenal for Chagas disease. The aim of this study was to evaluate the effect of allopurinol in association with nitroheterocyclic compounds on infection with the Y strain of Trypanosoma cruzi.

    Ana Lia Mazzeti, Lívia de F. Diniz, Karolina R. Gonçalves, Ruan Schott WonDollinger, Tassiane Assíria, Isabela Ribeiro, Maria T. Bahia
  • Mechanisms of Action: Physiological Effects
    In Vitro Efficacies of Nitazoxanide and Other Thiazolides against Neospora caninum Tachyzoites Reveal Antiparasitic Activity Independent of the Nitro Group
    Marco Esposito, Rebecca Stettler, Shelley L. Moores, Chandrakala Pidathala, Norbert Müller, Andrew Stachulski, Neil G. Berry, Jean-Francois Rossignol, Andrew Hemphill
  • Experimental Therapeutics
    Trypanocidal Activity of Melamine-Based Nitroheterocycles
    Mhairi L. Stewart, Gorka Jimenez Bueno, Alessandro Baliani, Burkhard Klenke, Reto Brun, Janice M. Brock, Ian H. Gilbert, Michael P. Barrett
  • Susceptibility
    In Vitro Activities of Position 2 Substitution-Bearing 6-Nitro- and 6-Amino-Benzothiazoles and Their Corresponding Anthranilic Acid Derivatives against Leishmania infantum and Trichomonas vaginalis
    Florence Delmas, Carole Di Giorgio, Maxime Robin, Nadine Azas, Monique Gasquet, Claire Detang, Muriel Costa, Pierre Timon-David, Jean-Pierre Galy
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