nitrofurans
Mechanisms of ResistanceNovel 5-Nitrofuran-Activating Reductase in Escherichia coliThe global spread of multidrug-resistant enterobacteria warrants new strategies to combat these pathogens. One possible approach is the reconsideration of “old” antimicrobials, which remain effective after decades of use. Synthetic 5-nitrofurans such as furazolidone, nitrofurantoin, and nitrofurazone are such a class of antimicrobial drugs.
- Mechanisms of Action: Physiological EffectsComputer-Aided Identification of Recognized Drugs as Pseudomonas aeruginosa Quorum-Sensing Inhibitors
- Mechanisms of Action: Physiological EffectsEnzymes Associated with Reductive Activation and Action of Nitazoxanide, Nitrofurans, and Metronidazole in Helicobacter pylori