Nystatin

Chemistry; Biosynthesis
Nystatin Biosynthesis and Transport: nysH and nysG Genes Encoding a Putative ABC Transporter System in Streptomyces noursei ATCC 11455 Are Required for Efficient Conversion of 10-Deoxynystatin to Nystatin
Håvard Sletta, Sven E. F. Borgos, Per Bruheim, Olga N. Sekurova, Hans Grasdalen, Randi Aune, Trond E. Ellingsen, Sergey B. Zotchev
Mechanisms of Action: Physiological Effects
Nystatin Induces Secretion of Interleukin (IL)-1β, IL-8, and Tumor Necrosis Factor Alpha by a Toll-Like Receptor-Dependent Mechanism
Raymund R. Razonable, Martin Henault, Harold L. Watson, Carlos V. Paya
Clinical Therapeutics
Liposomal Nystatin in Patients with Invasive Aspergillosis Refractory to or Intolerant of Amphotericin B
Fritz Offner, Vladimir Krcmery, Marc Boogaerts, Chantal Doyen, Dan Engelhard, Patricia Ribaud, Catherine Cordonnier, Ben de Pauw, Simon Durrant, Jean-Pierre Marie, Philippe Moreau, Harry Guiot, George Samonis, Richard Sylvester, Raoul Herbrecht
and the EORTC Invasive Fungal Infections Group
Pharmacology
Comparative Drug Disposition, Urinary Pharmacokinetics, and Renal Effects of Multilamellar Liposomal Nystatin and Amphotericin B Deoxycholate in Rabbits
Andreas H. Groll, Diana Mickiene, Vidmantas Petraitis, Ruta Petraitiene, Raul M. Alfaro, Christine King, Stephen C. Piscitelli, Thomas J. Walsh
Susceptibility
In Vitro Activities of Free and Lipid Formulations of Amphotericin B and Nystatin against Clinical Isolates of Coccidioides immitis at Various Saprobic Stages
Gloria M. González, Rolando Tijerina, Deanna A. Sutton, John R. Graybill, Michael G. Rinaldi
Susceptibility
Differential Antifungal Activity of Isomeric Forms of Nystatin
Luis Ostrosky-Zeichner, Scott Bazemore, Victor L. Paetznick, Jose R. Rodriguez, Enuo Chen, Tom Wallace, Paul Cossum, John H. Rex
Pharmacology
In Vitro Pharmacodynamic Characteristics of Nystatin Including Time-Kill and Postantifungal Effect
Shana M. Gunderson, Holly Hoffman, Erika J. Ernst, Michael A. Pfaller, Michael E. Klepser
Pharmacology
Compartmental Pharmacokinetics and Tissue Distribution of Multilamellar Liposomal Nystatin in Rabbits
Andreas H. Groll, Diana Mickiene, Kathy Werner, Ruta Petraitiene, Vidmantas Petraitis, Myrna Calendario, Aida Field-Ridley, Jeremy Crisp, Stephen C. Piscitelli, Thomas J. Walsh
Experimental Therapeutics
Dose Range Evaluation of Liposomal Nystatin and Comparisons with Amphotericin B and Amphotericin B Lipid Complex in Temporarily Neutropenic Mice Infected with an Isolate of Aspergillus fumigatus with Reduced Susceptibility to Amphotericin B
David W. Denning, Peter Warn
Experimental Therapeutics
Safety and Efficacy of Multilamellar Liposomal Nystatin against Disseminated Candidiasis in Persistently Neutropenic Rabbits
Andreas H. Groll, Vidmantas Petraitis, Ruta Petraitiene, Aida Field-Ridley, Myrna Calendario, John Bacher, Stephen C. Piscitelli, Thomas J. Walsh

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Nystatin

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