oxazolidinones

Letter to the Editor
Deletion of One 23S rRNA Gene (rrl) Copy Contributes to the Development of Linezolid Resistance in Staphylococcus warneri
Caroline Rouard, Florence Doucet-Populaire, Christelle Guillet-Caruba, Millie Villet, Nadège Bourgeois-Nicolaos
Experimental Therapeutics
In Vitro and In Vivo Activities of Contezolid (MRX-I) against Mycobacterium tuberculosis
Carolyn Shoen, Michelle DeStefano, Barry Hafkin, Michael Cynamon
Pharmacology
Mitochondrial Alterations (Inhibition of Mitochondrial Protein Expression, Oxidative Metabolism, and Ultrastructure) Induced by Linezolid and Tedizolid at Clinically Relevant Concentrations in Cultured Human HL-60 Promyelocytes and THP-1 Monocytes
Tamara V. Milosevic, Valéry L. Payen, Pierre Sonveaux, Giulio G. Muccioli, Paul M. Tulkens, Françoise Van Bambeke
Open Access

Mechanisms of Resistance
In Vitro Isolation and Characterization of Oxazolidinone-Resistant Mycobacterium tuberculosis
Matthew B. McNeil, Devon D. Dennison, Catherine D. Shelton, Tanya Parish
Clinical Therapeutics
Population Pharmacokinetics of AZD-5847 in Adults with Pulmonary Tuberculosis
Abdullah Alsultan, Jennifer J. Furin, Jeannine Du Bois, Elana van Brakel, Phalkun Chheng, Amour Venter, Bonnie Thiel, Sara A. Debanne, W. Henry Boom, Andreas H. Diacon, John L. Johnson, Charles A. Peloquin
Susceptibility
Activity of LCB01-0371, a Novel Oxazolidinone, against Mycobacterium abscessus
Tae Sung Kim, Jin Ho Choe, Young Jae Kim, Chul-Su Yang, Hyun-Jin Kwon, Jinsun Jeong, Guehye Kim, Da Eun Park, Eun-Kyeong Jo, Young-Lag Cho, Jichan Jang
Mechanisms of Resistance
Different Resistance Mechanisms for Cadazolid and Linezolid in Clostridium difficile Found by Whole-Genome Sequencing Analysis
Patrick Caspers, Hans H. Locher, Philippe Pfaff, Sarah Diggelmann, Georg Rueedi, Daniel Bur, Daniel Ritz
Epidemiology and Surveillance
Five-Year Summary of In Vitro Activity and Resistance Mechanisms of Linezolid against Clinically Important Gram-Positive Cocci in the United States from the LEADER Surveillance Program (2011 to 2015)
Michael A. Pfaller, Rodrigo E. Mendes, Jennifer M. Streit, Patricia A. Hogan, Robert K. Flamm
Clinical Therapeutics
Single- and Multiple-Dose Study To Determine the Safety, Tolerability, Pharmacokinetics, and Food Effect of Oral MRX-I versus Linezolid in Healthy Adult Subjects
Paul B. Eckburg, Yigong Ge, Barry Hafkin
Open Access

Susceptibility
In Vitro Activities of MCB3681 and Eight Comparators against Clostridium difficile Isolates with Known Ribotypes and Diverse Geographical Spread
Jane Freeman, Sally Pilling, Jonathan Vernon, Mark H. Wilcox

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