peptidoglycan amidation
Mechanisms of ResistanceRole of MurT C-Terminal Domain in the Amidation of Staphylococcus aureus PeptidoglycanGlutamate amidation, a secondary modification of the peptidoglycan, was first identified in Staphylococcus aureus. It is catalyzed by the protein products of the murT and gatD genes, which are conserved and colocalized in the genomes of most sequenced Gram-positive bacterial species. The MurT-GatD complex is required for cell viability, full...