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Peritonitis

  • Analysis of Paradoxical Efficacy of Carbapenems against Carbapenemase-Producing <span class="named-content genus-species" id="named-content-1">Escherichia coli</span> in a Murine Model of Lethal Peritonitis
    Experimental Therapeutics
    Analysis of Paradoxical Efficacy of Carbapenems against Carbapenemase-Producing Escherichia coli in a Murine Model of Lethal Peritonitis

    The clinical benefit of carbapenems against carbapenemase-producing Enterobacteriaceae (CPE) remains in question. MICs of imipenem (IMP) and ertapenem (ERT) against isogenic derivatives of the wild-type strain Escherichia coli CFT073 producing KPC-3, OXA-48, or NDM-1 were 0.25, 2, 16, and 64 mg/liter for IMP and 0.008, 0.5, 8, and 64 mg/liter for ERT,...

    Ariane Roujansky, Victoire de Lastours, François Guérin, Françoise Chau, Geoffrey Cheminet, Laurent Massias, Vincent Cattoir, Bruno Fantin
  • Open Access
    Mechanisms of Action: Physiological Effects
    Combined Systems Approaches Reveal a Multistage Mode of Action of a Marine Antimicrobial Peptide against Pathogenic Escherichia coli and Its Protective Effect against Bacterial Peritonitis and Endotoxemia
    Xiumin Wang, Da Teng, Ruoyu Mao, Na Yang, Ya Hao, Jianhua Wang
  • Experimental Therapeutics
    Plectasin Shows Intracellular Activity against Staphylococcus aureus in Human THP-1 Monocytes and in a Mouse Peritonitis Model
    Karoline Sidelmann Brinch, Anne Sandberg, Pierre Baudoux, Françoise Van Bambeke, Paul M. Tulkens, Niels Frimodt-Møller, Niels Høiby, Hans-Henrik Kristensen
  • Experimental Therapeutics
    Intracellular Activity of Antibiotics against Staphylococcus aureus in a Mouse Peritonitis Model
    Anne Sandberg, Jonas H. R. Hessler, Robert L. Skov, Jens Blom, Niels Frimodt-Møller
  • Clinical Therapeutics
    Antibacterial Efficacy of R-Type Pyocins towards Pseudomonas aeruginosa in a Murine Peritonitis Model
    Dean Scholl, David W. Martin
  • Experimental Therapeutics
    Pneumococcal LytA Autolysin, a Potent Therapeutic Agent in Experimental Peritonitis-Sepsis Caused by Highly β-Lactam-Resistant Streptococcus pneumoniae
    Violeta Rodríguez-Cerrato, Pedro García, Lorena Huelves, Ernesto García, Gema del Prado, Matilde Gracia, Carmen Ponte, Rubens López, Francisco Soriano
  • Experimental Therapeutics
    Rapid Bactericidal Activity of Daptomycin against Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Peritonitis in Mice as Measured with Bioluminescent Bacteria
    Lawrence I. Mortin, Tongchuan Li, Andrew D. G. Van Praagh, Shuxin Zhang, Xi-Xian Zhang, Jeff D. Alder
  • Experimental Therapeutics
    Microdialysis Study of Imipenem Distribution in the Intraperitoneal Fluid of Rats with or without Experimental Peritonitis
    Sandrine Lefeuvre, Sandrine Marchand, Isabelle Lamarche, Olivier Mimoz, William Couet
  • Experimental Therapeutics
    Systemic Antibacterial Activity of Novel Synthetic Cyclic Peptides
    Véronique Dartois, Jorge Sanchez-Quesada, Edelmira Cabezas, Ellen Chi, Chad Dubbelde, Carrie Dunn, Juan Granja, Colleen Gritzen, Dana Weinberger, M. Reza Ghadiri, Thomas R. Parr
  • Experimental Therapeutics
    Peptide Nucleic Acid Antisense Oligomer as a Therapeutic Strategy against Bacterial Infection: Proof of Principle Using Mouse Intraperitoneal Infection
    Xin-Xing Tan, Jeffrey K. Actor, Yin Chen

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