persister

  • Zebrafish Embryo Model for Assessment of Drug Efficacy on Mycobacterial Persisters
    Experimental Therapeutics
    Zebrafish Embryo Model for Assessment of Drug Efficacy on Mycobacterial Persisters

    Tuberculosis continues to kill millions of people each year. The main difficulty in eradication of the disease is the prolonged duration of treatment, which takes at least 6 months. Persister cells have long been associated with failed treatment and disease relapse because of their phenotypical, though transient, tolerance to drugs. By targeting these persisters, the duration of treatment could be shortened, leading to improved...

    Susanna Commandeur, Nino Iakobachvili, Marion Sparrius, Mariam Mohamed Nur, Galina V. Mukamolova, Wilbert Bitter
  • Experimental Therapeutics
    Triclosan Is an Aminoglycoside Adjuvant for Eradication of Pseudomonas aeruginosa Biofilms
    Michael M. Maiden, Alessandra M. Agostinho Hunt, Mitchell P. Zachos, Jacob A. Gibson, Martin E. Hurwitz, Martha H. Mulks, Christopher M. Waters
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