PK/PD

Open Access

Pharmacology
Pharmacological Basis of CD101 Efficacy: Exposure Shape Matters
Elizabeth A. Lakota, Justin C. Bader, Voon Ong, Ken Bartizal, Lynn Miesel, David R. Andes, Sujata M. Bhavnani, Christopher M. Rubino, Paul G. Ambrose, Alexander J. Lepak
Clinical Therapeutics
Population Pharmacokinetics of High-Dose Continuous-Infusion Meropenem and Considerations for Use in the Treatment of Infections Due to KPC-Producing Klebsiella pneumoniae
Piergiorgio Cojutti, Assunta Sartor, Elda Righi, Claudio Scarparo, Matteo Bassetti, Federico Pea
Pharmacology
In Vivo Pharmacokinetics and Pharmacodynamics of ZTI-01 (Fosfomycin for Injection) in the Neutropenic Murine Thigh Infection Model against Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa
Alexander J. Lepak, Miao Zhao, Brian VanScoy, Daniel S. Taylor, Evelyn Ellis-Grosse, Paul G. Ambrose, David R. Andes
Clinical Therapeutics
In Vivo Pharmacokinetic and Pharmacodynamic Profiles of Antofloxacin against Klebsiella pneumoniae in a Neutropenic Murine Lung Infection Model
Yu-Feng Zhou, Meng-Ting Tao, Wei Huo, Xiao-Ping Liao, Jian Sun, Ya-Hong Liu
Pharmacology
New Polymyxin B Dosing Strategies To Fortify Old Allies in the War against KPC-2-Producing Klebsiella pneumoniae
Zackery P. Bulman, Michael J. Satlin, Liang Chen, Barry N. Kreiswirth, Beom Soo Shin, Thomas J. Walsh, Patricia N. Holden, Alan Forrest, Roger L. Nation, Jian Li, Brian T. Tsuji
Experimental Therapeutics
Pharmacodynamics of Ceftaroline plus Ampicillin against Enterococcus faecalis in an In Vitro Pharmacokinetic/Pharmacodynamic Model of Simulated Endocardial Vegetations
Brian J. Werth, Laura M. Shireman

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