polymyxin B

Clinical Therapeutics
Population Pharmacokinetics of Intravenous Polymyxin B from Clinical Samples
Christine J. Kubin, Brian C. Nelson, Cristina Miglis, Marc H. Scheetz, Nathaniel J. Rhodes, Sean N. Avedissian, Serge Cremers, Michael T. Yin
Open Access

Pharmacology
Evaluation of Activity and Emergence of Resistance of Polymyxin B and ZTI-01 (Fosfomycin for Injection) against KPC-Producing Klebsiella pneumoniae
John K. Diep, Rajnikant Sharma, Evelyn J. Ellis-Grosse, Cely S. Abboud, Gauri G. Rao
Clinical Therapeutics
Severe Infusion-Related Adverse Events and Renal Failure in Patients Receiving High-Dose Intravenous Polymyxin B
Josiane F. John, Diego R. Falci, Maria Helena Rigatto, Renata D. Oliveira, Thaysa G. Kremer, Alexandre P. Zavascki
Open Access

Experimental Therapeutics
SPR741, an Antibiotic Adjuvant, Potentiates the In Vitro and In Vivo Activity of Rifampin against Clinically Relevant Extensively Drug-Resistant Acinetobacter baumannii
Daniel V. Zurawski, Alexandria A. Reinhart, Yonas A. Alamneh, Michael J. Pucci, Yuanzheng Si, Rania Abu-Taleb, Jonathan P. Shearer, Samandra T. Demons, Stuart D. Tyner, Troy Lister
Letter to the Editor
Evaluation of Urinary KIM-1 for Prediction of Polymyxin B-Induced Nephrotoxicity
Jessica T. Babic, Pooja Manchandani, Kimberly R. Ledesma, Vincent H. Tam
Pharmacology
Aerosolized Polymyxin B for Treatment of Respiratory Tract Infections: Determination of Pharmacokinetic-Pharmacodynamic Indices for Aerosolized Polymyxin B against Pseudomonas aeruginosa in a Mouse Lung Infection Model
Yu-Wei Lin, Qi Zhou, Nikolas J. Onufrak, Veronika Wirth, Ke Chen, Jiping Wang, Alan Forrest, Hak-Kim Chan, Jian Li
Susceptibility
Potentiation of Antibiotic Activity by a Novel Cationic Peptide: Potency and Spectrum of Activity of SPR741
David Corbett, Andrew Wise, Tara Langley, Kirsty Skinner, Emily Trimby, Stephen Birchall, Alain Dorali, Stephanie Sandiford, Jennifer Williams, Peter Warn, Martti Vaara, Troy Lister
Pharmacology
In Vitro Assessment of Combined Polymyxin B and Minocycline Therapy against Klebsiella pneumoniae Carbapenemase (KPC)-Producing K. pneumoniae
Dennis Huang, Brenda Yu, John K. Diep, Rajnikant Sharma, Michael Dudley, Jussimara Monteiro, Keith S. Kaye, Jason M. Pogue, Cely Saad Abboud, Gauri G. Rao
Letter to the Editor
Critical Need for Clarity in Polymyxin B Dosing
Nikolas J. Onufrak, Gauri G. Rao, Alan Forrest, Jason M. Pogue, Marc H. Scheetz, Roger L. Nation, Jian Li, Keith S. Kaye
Pharmacology
Role of Renal Drug Exposure in Polymyxin B-Induced Nephrotoxicity
Pooja Manchandani, Jian Zhou, Jessica T. Babic, Kimberly R. Ledesma, Luan D. Truong, Vincent H. Tam

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