polymyxin B

Clinical Therapeutics
Nephrotoxicity in Patients with or without Cystic Fibrosis Treated with Polymyxin B Compared to Colistin
Ryan L. Crass, W. Cliff Rutter, Donna R. Burgess, Craig A. Martin, David S. Burgess
Pharmacology
Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin
Zackery P. Bulman, Neang S. Ly, Justin R. Lenhard, Patricia N. Holden, Jürgen B. Bulitta, Brian T. Tsuji
Pharmacology
New Polymyxin B Dosing Strategies To Fortify Old Allies in the War against KPC-2-Producing Klebsiella pneumoniae
Zackery P. Bulman, Michael J. Satlin, Liang Chen, Barry N. Kreiswirth, Beom Soo Shin, Thomas J. Walsh, Patricia N. Holden, Alan Forrest, Roger L. Nation, Jian Li, Brian T. Tsuji
Minireview
Nephrotoxicity of Polymyxins: Is There Any Difference between Colistimethate and Polymyxin B?
Alexandre P. Zavascki, Roger L. Nation
Pharmacology
High-Dose Ampicillin-Sulbactam Combinations Combat Polymyxin-Resistant Acinetobacter baumannii in a Hollow-Fiber Infection Model
Justin R. Lenhard, Nicholas M. Smith, Zackery P. Bulman, Xun Tao, Visanu Thamlikitkul, Beom S. Shin, Roger L. Nation, Jian Li, Jürgen B. Bulitta, Brian T. Tsuji
Pharmacology
Polymyxin B in Combination with Rifampin and Meropenem against Polymyxin B-Resistant KPC-Producing Klebsiella pneumoniae
John K. Diep, David M. Jacobs, Rajnikant Sharma, Jenna Covelli, Dana R. Bowers, Thomas A. Russo, Gauri G. Rao
Pharmacology
Dosing and Pharmacokinetics of Polymyxin B in Patients with Renal Insufficiency
Visanu Thamlikitkul, Yanina Dubrovskaya, Pooja Manchandani, Thundon Ngamprasertchai, Adhiratha Boonyasiri, Jessica T. Babic, Vincent H. Tam
Susceptibility
Evaluating Polymyxin B-Based Combinations against Carbapenem-Resistant Escherichia coli in Time-Kill Studies and in a Hollow-Fiber Infection Model
Yiying Cai, Tze-Peng Lim, Jocelyn Qi-Min Teo, Suranthran Sasikala, Eric Chun Yong Chan, Yan Jun Hong, Winnie Lee, Thean Yen Tan, Thuan Tong Tan, Tse Hsien Koh, Li Yang Hsu, Andrea L. Kwa
Mechanisms of Resistance
Adaptive Resistance to the “Last Hope” Antibiotics Polymyxin B and Colistin in Pseudomonas aeruginosa Is Mediated by the Novel Two-Component Regulatory System ParR-ParS
Lucía Fernández, W. James Gooderham, Manjeet Bains, Joseph B. McPhee, Irith Wiegand, Robert E. W. Hancock
Mechanisms of Action: Physiological Effects
A Novel Polymyxin Derivative That Lacks the Fatty Acid Tail and Carries Only Three Positive Charges Has Strong Synergism with Agents Excluded by the Intact Outer Membrane
Martti Vaara, Osmo Siikanen, Juha Apajalahti, John Fox, Niels Frimodt-Møller, Hui He, Anima Poudyal, Jian Li, Roger L. Nation, Timo Vaara

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