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Pseudomonas Infections

  • Mechanisms of Resistance
    Molecular Characterization of Carbapenemase-Producing Pseudomonas aeruginosa of Czech Origin and Evidence for Clonal Spread of Extensively Resistant Sequence Type 357 Expressing IMP-7 Metallo-β-Lactamase
    Costas C. Papagiannitsis, Matej Medvecky, Katerina Chudejova, Anna Skalova, Veronika Rotova, Petra Spanelova, Vladislav Jakubu, Helena Zemlickova, Jaroslav Hrabak
    and on behalf of Czech Participants of the European Antimicrobial Resistance Surveillance Network
  • Experimental Therapeutics
    An Antipersister Strategy for Treatment of Chronic Pseudomonas aeruginosa Infections
    Martina Koeva, Alina D. Gutu, Wesley Hebert, Jeffrey D. Wager, Lael M. Yonker, George A. O'Toole, Frederick M. Ausubel, Samuel M. Moskowitz, Diane Joseph-McCarthy
  • Pharmacology
    Evaluation of Pharmacokinetic/Pharmacodynamic Model-Based Optimized Combination Regimens against Multidrug-Resistant Pseudomonas aeruginosa in a Murine Thigh Infection Model by Using Humanized Dosing Schemes
    Rajbharan Yadav, Jürgen B. Bulitta, Jiping Wang, Roger L. Nation, Cornelia B. Landersdorfer
  • Pharmacology
    Aminoglycoside Concentrations Required for Synergy with Carbapenems against Pseudomonas aeruginosa Determined via Mechanistic Studies and Modeling
    Rajbharan Yadav, Jürgen B. Bulitta, Elena K. Schneider, Beom Soo Shin, Tony Velkov, Roger L. Nation, Cornelia B. Landersdorfer
  • Mechanisms of Resistance
    Emergence of Ceftolozane-Tazobactam-Resistant Pseudomonas aeruginosa during Treatment Is Mediated by a Single AmpC Structural Mutation
    Shawn H. MacVane, Ruchi Pandey, Lisa L. Steed, Barry N. Kreiswirth, Liang Chen
  • Experimental Therapeutics
    Impact of Type III Secretion Effectors and of Phenoxyacetamide Inhibitors of Type III Secretion on Abscess Formation in a Mouse Model of Pseudomonas aeruginosa Infection
    Bryan J. Berube, Katherine R. Murphy, Matthew C. Torhan, Nicholas O. Bowlin, John D. Williams, Terry L. Bowlin, Donald T. Moir, Alan R. Hauser
  • Clinical Therapeutics
    Pharmacokinetic-Pharmacodynamic Target Attainment Analyses To Determine Optimal Dosing of Ceftazidime-Avibactam for the Treatment of Acute Pulmonary Exacerbations in Patients with Cystic Fibrosis
    Timothy J. Bensman, Joshua Wang, Jordanna Jayne, Lynn Fukushima, Adupa P. Rao, David Z. D'Argenio, Paul M. Beringer
  • Susceptibility
    Multicenter Evaluation of Ceftazidime-Avibactam and Ceftolozane-Tazobactam Inhibitory Activity against Meropenem-Nonsusceptible Pseudomonas aeruginosa from Blood, Respiratory Tract, and Wounds
    Mordechai Grupper, Christina Sutherland, David P. Nicolau
  • Experimental Therapeutics
    A Low-Molecular-Weight Alginate Oligosaccharide Disrupts Pseudomonal Microcolony Formation and Enhances Antibiotic Effectiveness
    Manon F. Pritchard, Lydia C. Powell, Alison A. Jack, Kate Powell, Konrad Beck, Hannah Florance, Julian Forton, Philip D. Rye, Arne Dessen, Katja E. Hill, David W. Thomas
  • Clinical Therapeutics
    The Nonantibiotic Macrolide EM703 Improves Survival in a Model of Quinolone-Treated Pseudomonas aeruginosa Airway Infection
    Gopinath Kasetty, Ravi K. V. Bhongir, Praveen Papareddy, Heiko Herwald, Arne Egesten

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