Pyrrolidines

Open Access

Antiviral Agents
In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS5A Inhibitor Pibrentasvir
Teresa I. Ng, Preethi Krishnan, Tami Pilot-Matias, Warren Kati, Gretja Schnell, Jill Beyer, Thomas Reisch, Liangjun Lu, Tatyana Dekhtyar, Michelle Irvin, Rakesh Tripathi, Clarence Maring, John T. Randolph, Rolf Wagner, Christine Collins
Mechanisms of Action: Physiological Effects
Probing the Differential Interactions of Quinazolinedione PD 0305970 and Quinolones with Gyrase and Topoisomerase IV
Xiao-Su Pan, Katherine A. Gould, L. Mark Fisher
Antiviral Agents
Activity of the Oral Neuraminidase Inhibitor A-322278 against the Oseltamivir-Resistant H274Y (A/H1N1) Influenza Virus Mutant in Mice
Mariana Baz, Yacine Abed, Benjamin Nehmé, Guy Boivin
Experimental Therapeutics
Pyrrolidine Dithiocarbamate and Diethyldithiocarbamate Are Active against Growing and Nongrowing Persister Mycobacterium tuberculosis
Sean T. Byrne, Peihua Gu, Jiangbing Zhou, Steven M. Denkin, Curtis Chong, David Sullivan, Jun O. Liu, Ying Zhang
Pharmacology
Lack of Effect of DX-619, a Novel Des-Fluoro(6)-Quinolone, on Glomerular Filtration Rate Measured by Serum Clearance of Cold Iohexol
Nenad Sarapa, Prachi Wickremasingha, NanXiang Ge, Richard Weitzman, Merynda Fuellhart, Cindy Yen, Julia Lloyd-Parks
Susceptibility
Activity of DX-619 Compared to Other Agents against Viridans Group Streptococci, Streptococcus bovis, and Cardiobacterium hominis
Klaudia Kosowska-Shick, Kathy Smith, Tatiana Bogdanovich, Lois M. Ednie, Ronald N. Jones, Peter C. Appelbaum
Susceptibility
Molecular Characteristics and In Vitro Susceptibility to Antimicrobial Agents, Including the Des-Fluoro(6) Quinolone DX-619, of Panton-Valentine Leucocidin-Positive Methicillin-Resistant Staphylococcus aureus Isolates from the Community and Hospitals
Tatsuo Yamamoto, Soshi Dohmae, Kohei Saito, Taketo Otsuka, Tomomi Takano, Megumi Chiba, Katsuko Fujikawa, Mayumi Tanaka
Susceptibility
In Vitro Antianaerobic Activity of DX-619, a New Des-Fluoro(6) Quinolone
Kaori Tanaka, Hiroshige Mikamo, Ken'ichi Nakao, Kunitomo Watanabe
Mechanisms of Action: Physiological Effects
Intracellular Penetration and Activity of DX-619 in Human Polymorphonuclear Leukocytes
Isabel García, Sofía Ballesta, Concepción Murillo, Evelio J. Perea, Álvaro Pascual
Susceptibility
In Vitro Activities of DX-619 and Comparison Quinolones against Gram-Positive Cocci
Paul A. Wickman, Jennifer A. Black, Ellen Smith Moland, Kenneth S. Thomson

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Pyrrolidines

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