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Pyrrolidines

  • Open Access
    Antiviral Agents
    In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS5A Inhibitor Pibrentasvir
    Teresa I. Ng, Preethi Krishnan, Tami Pilot-Matias, Warren Kati, Gretja Schnell, Jill Beyer, Thomas Reisch, Liangjun Lu, Tatyana Dekhtyar, Michelle Irvin, Rakesh Tripathi, Clarence Maring, John T. Randolph, Rolf Wagner, Christine Collins
  • Mechanisms of Action: Physiological Effects
    Probing the Differential Interactions of Quinazolinedione PD 0305970 and Quinolones with Gyrase and Topoisomerase IV
    Xiao-Su Pan, Katherine A. Gould, L. Mark Fisher
  • Antiviral Agents
    Activity of the Oral Neuraminidase Inhibitor A-322278 against the Oseltamivir-Resistant H274Y (A/H1N1) Influenza Virus Mutant in Mice
    Mariana Baz, Yacine Abed, Benjamin Nehmé, Guy Boivin
  • Experimental Therapeutics
    Pyrrolidine Dithiocarbamate and Diethyldithiocarbamate Are Active against Growing and Nongrowing Persister Mycobacterium tuberculosis
    Sean T. Byrne, Peihua Gu, Jiangbing Zhou, Steven M. Denkin, Curtis Chong, David Sullivan, Jun O. Liu, Ying Zhang
  • Pharmacology
    Lack of Effect of DX-619, a Novel Des-Fluoro(6)-Quinolone, on Glomerular Filtration Rate Measured by Serum Clearance of Cold Iohexol
    Nenad Sarapa, Prachi Wickremasingha, NanXiang Ge, Richard Weitzman, Merynda Fuellhart, Cindy Yen, Julia Lloyd-Parks
  • Susceptibility
    Activity of DX-619 Compared to Other Agents against Viridans Group Streptococci, Streptococcus bovis, and Cardiobacterium hominis
    Klaudia Kosowska-Shick, Kathy Smith, Tatiana Bogdanovich, Lois M. Ednie, Ronald N. Jones, Peter C. Appelbaum
  • Susceptibility
    Molecular Characteristics and In Vitro Susceptibility to Antimicrobial Agents, Including the Des-Fluoro(6) Quinolone DX-619, of Panton-Valentine Leucocidin-Positive Methicillin-Resistant Staphylococcus aureus Isolates from the Community and Hospitals
    Tatsuo Yamamoto, Soshi Dohmae, Kohei Saito, Taketo Otsuka, Tomomi Takano, Megumi Chiba, Katsuko Fujikawa, Mayumi Tanaka
  • Susceptibility
    In Vitro Antianaerobic Activity of DX-619, a New Des-Fluoro(6) Quinolone
    Kaori Tanaka, Hiroshige Mikamo, Ken'ichi Nakao, Kunitomo Watanabe
  • Mechanisms of Action: Physiological Effects
    Intracellular Penetration and Activity of DX-619 in Human Polymorphonuclear Leukocytes
    Isabel García, Sofía Ballesta, Concepción Murillo, Evelio J. Perea, Álvaro Pascual
  • Susceptibility
    In Vitro Activities of DX-619 and Comparison Quinolones against Gram-Positive Cocci
    Paul A. Wickman, Jennifer A. Black, Ellen Smith Moland, Kenneth S. Thomson

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